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Clara Bonnet

@bonnetc.bsky.social

21 followers 58 following 0 posts

Post-doctoral fellow at Daniel Durocher lab

Posts Replies Media

Reposted by Clara Bonnet

Daniel Durocher @durocher1.bsky.social · 25/08/2026

New work from the lab! We report that DDIAS is a downstream effector of CIP2A-TOPBP1 in mitosis that suppresses ssDNA to preserve genome integrity. From the great @yiboxue.bsky.social and many collaborators! Free link: authors.elsevier.com/a/1nfiF3vVUP... Pay link: www.cell.com/molecular-ce...

Model of DDIAS acting in mitosis to suppress ssDNA

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Reposted by Clara Bonnet

Daniel Durocher @durocher1.bsky.social · 10/09/2025

New work from the lab! 🔬 We report that DDIAS is a new component of the mitotic CIP2A-TOPBP1 pathway of genome maintenance. 1/n www.biorxiv.org/content/10.1...

biorxiv.org

Mitotic single-stranded DNA suppression by DDIAS

Incomplete DNA replication and chromosome breakage during mitosis pose major threats to chromosome segregation. The CIP2A-TOPBP1 complex acts to mitigate this peril, but its exact role is not yet unde...

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