Key Points. The fetal HSC state is permissive, with mixed in vitro output, whereas adult HSCs exhibit chromatin-level and functional myeloid biasFetal lymp

Cell differentiation is governed by dynamic changes in chromatin accessibility, and its dysregulation underlies multiple disease states. Prior to birth, development of the hematopoietic system constit...

We here provide key insights into the KMT2A::AFF1 pre-leukemic phase using a novel murine model, of critical importance to human disease initiation.

Lund University. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes positions of up to six years f...

Lund University. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes positions of up to six years f...

Leukemia - Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state

Tremblay Lab Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and ge...

ISEH 54th Annual Scientific Meeting

On March 8th every year, the achievements of women are celebrated worldwide in conjunction with International Women's Day. It highlights the...