Check out the pre-print for 'SPIN-seq' - short-read single-molecule DNA sequencing method to link protein-DNA interactions with sequence. 🧬
It's great to see my main DPhil project developed further!
www.biorxiv.org/content/10.1...
biorxiv.org
Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing
DNA sequence regulates complex reactions and protein-DNA interactions, yet sequence effects remain poorly understood due to the lack of direct, high-throughput approaches to study sequence-dependence ...
