iiinova — where your digital self keeps evolving

Reposted by Adam Nathan McShane

Journal of Experimental Medicine @jem.org · 07/09/2026

Our September cover (rupress.org/jem/issue/22... ) depicts a confocal image of Ramos B cells extracting surface-bound antigen from plasma membrane sheets. Sheets are labeled w/ fluorescent surrogate antigen (magenta); B cells are marked by CD19 (orange). See Berzosa et al. doi.org/10.1084/jem....

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Reposted by Adam Nathan McShane

Rockefeller University Press @rupress.org · 07/09/2026

@jem.org September cover (rupress.org/jem/issue/22... ) depicts a confocal image of Ramos B cells extracting surface-bound antigen from plasma membrane sheets. Sheets are labeled w/ fluorescent surrogate antigen (magenta); B cells are marked by CD19 (orange). Berzosa et al.: doi.org/10.1084/jem....

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Adam Nathan McShane @basicleukocyte.bsky.social · 07/09/2026

Thrilled to see one of my images featured on the cover! 🔬

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Adam Nathan McShane @basicleukocyte.bsky.social · 05/08/2026

Thank you to everyone involved, especially my co-first author Melibea Berzosa Suñer, Dessi Malinova, and our collaborators in the Persephone Borrow Lab, Nuffield Department of Medicine, University of Oxford, and Olav Andersen, Department of Biomedicine, Aarhus University

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Adam Nathan McShane @basicleukocyte.bsky.social · 05/08/2026

Loss of SorLA led to reduced peptide-MHC II presentation, and impaired humoral immune responses in vivo, highlighting how intracellular trafficking pathways can modulate immunity

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Adam Nathan McShane @basicleukocyte.bsky.social · 05/08/2026

Here, we characterise the role of intracellular trafficking receptor, SorLA, as a novel regulator of BCR-antigen trafficking. We find that SorLA interacts with the BCR, regulating BCR endocytosis and antigen-induced BCR degradation

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Adam Nathan McShane @basicleukocyte.bsky.social · 05/08/2026

🎉 Very excited to share that my first first-author paper is now out in the Journal of Experimental Medicine! (@jem.org, @rupress.org) doi.org/10.1084/jem.... 📹 Short video summary: www.youtube.com/watch?v=O0v8... @wwiem-qub.bsky.social @qubelfastofficial.bsky.social

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Reposted by Adam Nathan McShane

Rockefeller University Press @rupress.org · 04/08/2026

In @jem.org, Berzosa, @basicleukocyte.bsky.social, Malinova et al. identify SorLA as a key regulator of B cell receptor trafficking, which binds immunoglobulin and controls endosomal sorting. rupress.org/jem/article/... 🎥 Short video summary by McShane: youtu.be/O0v87xz-Bik

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Reposted by Adam Nathan McShane

Journal of Experimental Medicine @jem.org · 04/08/2026

Berzosa, @basicleukocyte.bsky.social, Malinova et al. identify SorLA as a key regulator of B cell receptor trafficking, which binds immunoglobulin and controls endosomal sorting. rupress.org/jem/article/... 🎥 Short video summary by McShane: youtu.be/O0v87xz-Bik

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Reposted by Adam Nathan McShane

Tolar Lab @tolarlab.bsky.social · 10/07/2026

The Tolar lab is looking for a part-time research technician. Come work with us on B-cell immunity! www.ucl.ac.uk/work-at-ucl/...

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Adam Nathan McShane @basicleukocyte.bsky.social · 23/12/2025

I officially graduated with my PhD from @qubelfastofficial.bsky.social last week! Thank you again to Dessi Malinova for your mentorship, and the Malinova Lab Group, my friends and family, and @wwiem-qub.bsky.social for your support <3

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Adam Nathan McShane @basicleukocyte.bsky.social · 07/12/2025

great catching up with everyone at #BSI25! always such a fun week

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Adam Nathan McShane @basicleukocyte.bsky.social · 02/12/2025

also go see @sarahdezperez.bsky.social's poster (P518) tomorrow (IgE PC tracing & characterisation)

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Adam Nathan McShane @basicleukocyte.bsky.social · 02/12/2025

at #BSI25 & interested in FDCs? come chat at my poster (P583) later! (FDC hands)

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Reposted by Adam Nathan McShane

Sara Hernández Pérez @sarahdezperez.bsky.social · 05/03/2025

Check the latest 'B cell Receptor Signaling: Methods and Protocols' book. Including Functional Assessment of B Cells In Vivo and Ex Vivo, Advanced Imaging and Gene Editing. link.springer.com/book/10.1007...

link.springer.com

B-Cell Receptor Signaling

This volume covers classical cell and molecular biology applications and state-of-the-art omics techniques for studying BCR signaling.

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Adam Nathan McShane @basicleukocyte.bsky.social · 08/12/2024

It's Dr. McShane, actually 🍾 Thank you to my examiners Prof. Martin Lowe & Dr. Rebecca Ingram, as well as my supervisor Dr. Dessi Malinova & the rest of the Malinova Lab @wwiem-qub.bsky.social @qubelfastofficial.bsky.social #PhDone

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Adam Nathan McShane @basicleukocyte.bsky.social · 20/11/2024

Had such a great time exploring Manchester & getting to learn some queer history, as well as being immersed in some excellent science - thanks again for organising!

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Reposted by Adam Nathan McShane

Matthew Sinton 🏳️‍🌈 @mcsinton.bsky.social · 18/11/2024

After 5 years, our first in-person event is happening! So grateful to @juanquintana.bsky.social and @alex-cocker.bsky.social for making this happen. And to @drtesutherland.bsky.social and @franzeprogatzky.bsky.social for all of their help!

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Reposted by Adam Nathan McShane

Matthew Sinton 🏳️‍🌈 @mcsinton.bsky.social · 17/11/2024

Making a starter pack of LGBTQ+ immunologists and need 8 people to create the pack. Don’t want to add people who haven’t requested to be added, so please let me know if you’d like including #Immunosky #PrideInSTEM 🏳️‍🌈🏳️‍⚧️

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Adam Nathan McShane @basicleukocyte.bsky.social · 17/11/2024

hello 🦋! Northern Irish postdoc @ Tolar Lab, UCL :) Looking forward to connecting with other immunologists, and people interested in DnD, bouldering, plants, baking, Europop, & language learning! #immunology

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