Reposted by Hayley Knox, PhD
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Excited to share our latest preprint!
www.biorxiv.org/content/10.1...
We developed a method to generate high-affinity binders against membrane proteins in their native-like environment!
🧪 #MembraneProteins #Nanobodies
biorxiv.org
Selection of nanobodies against liponanoparticle-embedded membrane proteins by yeast surface display
Single-domain antibodies, known as nanobodies (Nbs), are widely used in structural biology, therapeutics, and as molecular probes in biology and biotechnology. Nbs towards soluble proteins are routine...
