Reposted by Bart LarsenSteven Meisler @stevenmeisler.com · 15hThere are many MRI approaches for studying myelin. But which ones are reliable, how do they relate to each other, and how do they behave in gray vs white matter? In our new preprint, we introduce Myelin Imaging Reliability and ReprOducibility Resource (MIRROR) 🧠🪞 📄🔗 www.biorxiv.org/content/10.6... 12410
Bart Larsen @bart-larsen.bsky.social · 03/09/2026Woohoo! Congratulations @valeriejsydnor.bsky.social !!! 050
Reposted by Bart LarsenBene Ramirez @benediktramirez.bsky.social · 23/08/2026Excited to share our new preprint introducing Precision Confidence Mapping (PCM), a framework for estimating how confident we should be in individualized functional network assignments from resting-state fMRI. Why does this matter for precision neuromodulation? 🧵👇 www.biorxiv.org/content/10.6...biorxiv.org 13815
Reposted by Bart LarsenAhmad Beyh @ahmadbeyh.bsky.social · 24/08/2026⚠️ Preprint alert ⚠️ How does the brain's fixed anatomy support flexible function? We explore this using recurrent neural networks with increasing levels of brain-like constraints, comparing them to empirical fMRI activity. (1/8) www.biorxiv.org/content/10.6...biorxiv.orgGeometric constraints and cognitive inputs jointly shape emergent brain dynamics and topologyHow the brain's physical geometry gives rise to its flexible functional repertoire remains a central question in neuroscience. Here, we trained three classes of recurrent neural networks (RNNs) on a w... 14721
Reposted by Bart LarsenAshley Watts @ashleylwatts.bsky.social · 09/07/2026Excited to share a paper recently accepted at Nature Mental Health! 😄 For decades, we've assumed that covariance among psychopathology informs comorbidity. What if we’ve been wrong? 913461
Reposted by Bart LarsenHolly Sullivan-Toole @hollysully.bsky.social · 12/07/2026🚨 preprint alert !!! Emotional and physical abuse have dissociable impacts on punishment learning and task engagement during adolescence osf.io/preprints/ps... 1103
Reposted by Bart LarsenEvan Gordon @gordonneuro.bsky.social · 22/04/2026I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6... 14234122
Bart Larsen @bart-larsen.bsky.social · 21/04/2026Another fresh preprint from the lab! Menarche marks an inflection point for female brain and mental health trajectories. This milestone may identify a critical window for screening. This is an effect you don't need stats to see (though we did those too). Led by @carinaheller.bsky.social 🧵👇 0112
Reposted by Bart LarsenCarina Heller, Ph.D. @carinaheller.bsky.social · 21/04/2026🚨Preprint Alert 🧠 Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online! 👉 Preprint available here: www.biorxiv.org/content/10.6... 14825
Bart Larsen @bart-larsen.bsky.social · 21/04/2026Very excited to announce our new preprint, led by @hollysully.bsky.social, that presents, benchmarks, and validates a method to estimate brain iron content from routine fMRI scans! It comes complete with a BIDS app! Check out the preprint and thread below! doi.org/10.64898/202...biorxiv.org 072
Reposted by Bart LarsenThomas Yeo @bttyeo.bsky.social · 02/04/2026Updated preprint: doi.org/10.1101/2025... We have improved DELSSOME and showed that we can accelerate the estimation of two new biophysical models. By collating 12,005 individuals, we derive normative trajectories of cortical E/I ratio across the lifespan ...doi.org 12110
Reposted by Bart LarsenAudrey Luo @audreycluo.bsky.social · 02/03/2026We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, “Two Axes of White Matter Development”, is now out in @natcomms.nature.com! 🛣️🧠✨ 🔗 bit.ly/wm2axes 211147
Reposted by Bart LarsenJohn Holbein @johnholbein1.bsky.social · 08/01/2026“These findings provide clear evidence that data collected on MTurk simply cannot be trusted.” 11289107
Reposted by Bart LarsenHolly Sullivan-Toole @hollysully.bsky.social · 07/01/2026New paper & a thread on the results 👇 ‘Reward-specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression’ acamh-onlinelibrary-wiley-com.ezp3.lib.umn.edu/doi/full/10.... 42311
Reposted by Bart LarsenJoëlle Bagautdinova @joelleba.bsky.social · 05/01/2026Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels? Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202... Thread below 🧵doi.orgAnatomical White Matter Tracts Span the Cortical Hierarchy to Support Cognitive DiversityLong-range white matter (WM) tracts support cognition by enabling communication between distant cortical regions, which are organized along a hierarchy defined by the sensorimotor-to-association (S-A)... 23315
Bart Larsen @bart-larsen.bsky.social · 18/12/2025Very happy to share our paper on the "summer slide" in kid's cognitive test scores is out now in @pnas.org! We find a replicable dip in performance across multiple domains of cognition in >23,000 kids across 4 datasets! Check out the 🧵 from @ariellekeller.bsky.social below! 👇 0239
Reposted by Bart LarsenCleanthis Michael @clmich.bsky.social · 01/12/2025Excited to share our new review “Mapping interactions between adversity and neuroplasticity across development” in @cp-trendscognsci.bsky.social. We discuss how experience - particularly adversity - interacts with neuroplasticity during human development authors.elsevier.com/c/1mB5U4sIRv... 13212
Reposted by Bart LarsenDaeyeol Lee @ungteoriz.bsky.social · 02/12/2025Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology. pbs.jhu.edu/about/jobs/pbs.jhu.eduJobs | Psychological & Brain SciencesTenured/Tenure-track position in Cognitive Psychology Open Date Dec 01, 2025 Salary Range or Pay Grade The expected academic base salary range for this position is $110,000- $144,500 (Assistant Profes... 06958
Reposted by Bart LarsenGang Chen @gangchen6.bsky.social · 18/11/2025Is the “standard workflow” holding back fMRI analysis? Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die. 14013
Bart Larsen @bart-larsen.bsky.social · 12/11/2025I can't recommend this fantastic new review from @valeriejsydnor.bsky.social enough! It does an amazing job of synthesizing the current state of the literature and then looking forward to provide a fresh perspective on how to move this work forward in humans. Check it out! 071
Reposted by Bart LarsenMatt Cieslak @cieslakmatt.bsky.social · 11/11/2025After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:biorxiv.orgDiffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and ApplicationsThe landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo... 34428
Reposted by Bart LarsenThomas Lin Pedersen @thomasp85.com · 11/09/2025I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN. It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package. Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstatstidyverse.orgggplot2 4.0.0A new major version of ggplot2 has been released on CRAN. Find out what is new here. 9851281
Reposted by Bart LarsenDamien Fair @drdamienfair.bsky.social · 10/08/2025I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf... 16390136
Bart Larsen @bart-larsen.bsky.social · 09/07/2025This paper truly exemplifies what is possible in the modern era of neuroimaging data. A beautiful and extremely impressive piece of work from @valeriejsydnor.bsky.social that was a treat to contribute to. Check it out! 093
Reposted by Bart LarsenDamien Fair @drdamienfair.bsky.social · 29/06/2025OK, It is not just the HBCD release... docs.hbcdstudy.org It’s the ABCD Release time too! docs.abcdstudy.org nbdc-datahub.org That means the ABCC 3.0.0 is live!!! The largest release yet from the ABCD-BIDS Community Collection. This is going to be fun!! 👇 Let’s dig in. 12612
Reposted by Bart LarsenArielle Keller @ariellekeller.bsky.social · 22/04/2025Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠 #neuroskyence #neuroimaging #psychscisky 14214
Reposted by Bart LarsenThomas Yeo @bttyeo.bsky.social · 11/04/2025While the world burns, we cook up a new preprint! doi.org/10.1101/2025... Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N 110839
Bart Larsen @bart-larsen.bsky.social · 29/04/2025Awesome opening salvo from the lab of @lindenmp.bsky.social!! Super cool work that will stem many future directions! 031
Reposted by Bart LarsenNatalie Christie Peluso 🧠 @nataliepeluso.com · 01/04/2025Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇 #interoception 🧠🫀 #neuroskyence elifesciences.org/reviewed-pre...elifesciences.orgAge-related changes in “cortical” 1/f dynamics are linked to cardiac activity 0317
Reposted by Bart LarsenAlexandria Ocasio-Cortez @aoc.bsky.social · 22/03/2025Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back. This was the largest political gathering in Denver since Obama in 2008. Also bigger than the 2024 DNC. And the largest ever rally in Bernie’s career (and obviously, mine too). 331810588817797
Reposted by Bart LarsenAudrey Luo @audreycluo.bsky.social · 20/03/2025We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1... 1/n 1012352
Reposted by Bart LarsenRuss Poldrack @russpoldrack.org · 08/02/2025Great analysis of the indirect cost rate announcement by @stuartbuck.bsky.socialopen.substack.comIndirect Costs at NIH . . .I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night: 310042
Reposted by Bart LarsenMarc Coutanche @marccoutanche.bsky.social · 08/02/2025For those who don't know, here are very real research costs that directs cannot cover - all fall within indirects: the buildings we work in (upkeep, maintenance, cleaning, etc), utilities, IT infrastructure, human resources, administrative staff, security, and lots more 1166
Reposted by Bart LarsenJulia Moser @drjuliamoser.bsky.social · 10/01/2025Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠 55517
Reposted by Bart LarsenParker Singleton @parkersingleton.bsky.social · 10/01/2025Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data. 🔗 www.nature.com/articles/s44... 🧪🧵nature.comAn initiative for living evidence synthesis in clinical psychedelic research - Nature Mental HealthRenewed interest in psychedelics as treatments for mental disorders has recently emerged, but substantial challenges remain in obtaining evidence from available data to inform clinical decision-making... 36630
Reposted by Bart LarsenRick Betzel @richardfbetzel.bsky.social · 03/12/2024hey -- i'm hiring a postdoc! the ad will be up shortly, but looking for someone with network neuroscience experience (very broadly). the position isn't tied to any specific project/grant, so lots of flexibility in terms of what you'd actually *do*. hmu if you might be interested/want to learn more! 15249
Reposted by Bart LarsenKaidi Kang @kaidikang.bsky.social · 28/11/2024Thank you, Dr. Fair! It was really a rewarding experience for me to collaborate with your team from #MIDB! @drdamienfair.bsky.social @tervoclemmensb.bsky.social @bart-larsen.bsky.social Thank you for all your efforts and expertise you put into this work; they truly made this work better! 085
Reposted by Bart LarsenDamien Fair @drdamienfair.bsky.social · 27/11/2024Congratulations @kaidikang.bsky.social et al on their paper in Nature. Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more! If you are interested in optimizing study designs, take a look, it's a great read! www.nature.com/articles/s41...nature.comStudy design features increase replicability in brain-wide association studies - NatureOptimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association ... 03215
Reposted by Bart LarsenPennLINC @pennlinc.bsky.social · 22/11/2024We're excited to release new versions of our BIDS-Apps for processing and analyzing #dmri data, QSIPrep and QSIRecon! Our team has been working hard to prepare these pipelines to process infant data and bring them in line with the @nipreps.bsky.social ecosystem. #neuroimaging #nipreps #bids 1/10 13924
Reposted by Bart LarsenBrenden Tervo-Clemmens @tervoclemmensb.bsky.social · 21/11/2024👏👏👏 @ariellekeller.bsky.social et al. with cyclical GAMs, multi-dataset replication, and study planning relevance! 1163
Bart Larsen @bart-larsen.bsky.social · 21/11/2024Very happy with how this one turned out! This started as a curiosity, that built into a side project, and eventually into a very cool paper! This was also super fun to work on with @ariellekeller.bsky.social! Check out her thread below and the preprint here: osf.io/preprints/ps...osf.ioOSF 0216
Reposted by Bart LarsenArielle Keller @ariellekeller.bsky.social · 18/11/2024Super excited to share our official ACORN Lab website!! 🍁🧠 appliedcognitionlab.psychology.uconn.edu We are recruiting new team members at the undergraduate, graduate, and postdoctoral levels - join us! #Neuroskyence #neuroimaging #PsychSciSky #CogPsyc #ClinPsych #CogDev #devpsy #CogSciappliedcognitionlab.psychology.uconn.eduHome | Applied Cognition and Personalized Neuroscience LabWelcome to the Applied Cognition & Personalized Neuroscience Lab! The Applied Cognition and peRsonalized Neuroscience (ACORN) lab is a collabora ... 27430
Reposted by Bart LarsenShematologist, MD @shematologist.medsky.social · 19/11/2024Just your regular reminder that ~40% of menstruating adolescents (and likely an even higher proportion of adults) suffer from iron deficiency and yet we don’t universally screen. tinyurl.com/JAMAFetinyurl.comPrevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020This study examines prevalence of iron deficiency among females aged 12 to 21 years to inform future screening strategies for iron deficiency and iron-deficiency anemia. 2335874
Bart Larsen @bart-larsen.bsky.social · 04/01/2024🧠💡Postdoc opportunity! Interested in: 📈Adolescent neurodevelopment 🧲7T neuroimaging 🧬Biological influences on brain dev Join our team at UMN MIDB to investigate the interplay between iron, neurodevelopment, and mental health in adolescence! To apply: hr.myu.umn.edu/jobs/ext/359... 094