Reposted by Ayden Case
Research| Case et al. report that low-dose interleukin-2 clonally expands Tregs and maintains their suppressive program by bypassing BACH2 downregulation in patients with acute coronary syndrome from the LILACS trial.
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Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells following acute coronary syndrome - Nature Cardiovascular Research
By integrating single-cell transcriptomics and T cell receptor repertoire analyses of regulatory T (Treg) cells in a cohort of patients with acute coronary syndrome from the LILACS trial, Case et al. ...