iiinova — where your digital self keeps evolving

Aryan Taheri @aryantaheri.bsky.social · 31/07/2026

Happy to share my new paper from the @nogaleslab.bsky.social, combining #cryoEM and #cryoET to solve how Kinesin-4 KIF21B tail binds to microtubules! Our work shows how the specialized tails of KIF21 kinesins allow both #microtubule attachment and crosslinking. www.biorxiv.org/content/10.6...

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Aryan Taheri @aryantaheri.bsky.social · 30/07/2026

Excited to see our recent work on the structural mechanism of α/β-tubulin biogenesis featured on the #CryoSPARC blog! 🎉 Many thanks to the team at @structurabio.bsky.social Biotechnology for highlighting both the study and the #cryo-EM workflow that made these structures possible. Read more here:

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Reposted by Aryan Taheri

Nogales Lab @nogaleslab.bsky.social · 29/06/2026

Excited to share our new preprint with the Yildiz and Janke labs on how Ndc80 and Ska complexes cooperate on microtubules through a SKA3 tether and tubulin tail interface to stabilize attachment! Congrats to Ju and Ipsita for leading this exciting study! www.biorxiv.org/content/10.6...

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Reposted by Aryan Taheri

Nogales Lab @nogaleslab.bsky.social · 24/05/2026

Congrats to Ana Galic and Kevin Li, who just graduated with honors in MCB @berkeleymcb.bsky.social, and to the brand new Dr. Trinity Cookis @trinitycookis.bsky.social 👨‍🎓👩‍🎓👩‍🎓🤩. Very best wishes for your next endeavors 💝

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Aryan Taheri @aryantaheri.bsky.social · 08/05/2026

How do #tubulin dimers assemble and disassemble to form the #microtubule #cytoskeleton? Our recent #cryo-EM structures, published in #ScienceAdvances, demonstrate the processes of tubulin biogenesis and degradation. Click on the video and link below to learn more! www.science.org/doi/10.1126/...

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Aryan Taheri @aryantaheri.bsky.social · 07/05/2026

How does Taxol bind microtubules, and why do tubulin isoforms matter for its efficacy? In my recent commentary in @natchembio.nature.com, I discuss Luo et al.’s mechanistic insights and their implications for designing isoform-selective microtubule-targeting drugs. www.nature.com/articles/s41...

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Reposted by Aryan Taheri

Ivana Gasic @ivanagasic.bsky.social · 10/01/2026

New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.

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Reposted by Aryan Taheri

Nogales Lab @nogaleslab.bsky.social · 18/11/2025

Excited to share our new preprint in collaboration with Ahmet Yildiz's lab. Check out how our team uncovers a novel binding footprint and motor regulation mechanism for MAP9 Congrats to Burak Cetin and @aryantaheri.bsky.social www.biorxiv.org/content/10.1...

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