iiinova — where your digital self keeps evolving

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 18/02/2025

Have I been working with someone who says CTX this whole time? 😱

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 31/12/2024

Based on the pharmacokinetic studies I’ve read with oritavancin, I doubt it would have an issue staying above that MIC, one 1,200 mg dose seemingly gets to 100 mcg/mL in the serum as a peak. Those who actually use oritavancin (I haven’t) are free to correct me though! doi:10.1007/s40801-020-00188-6

040 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 31/12/2024

Not necessarily, but compared to other isolates identified by EUCAST, 0.125 mcg/mL is a higher MIC than the majority. It would depend on the site of infection and if > 0.125 mcg/mL concentration of oritavancin can get there adequately.

000 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 31/12/2024

There’s no direct ECOFF on EUCAST for oritavancin for E. faecium, however out of 320 observations, 41 had an MIC of 0.125 and only 8 were above that MIC. I’d say it’s on the higher end of comfort, but no great data for clinical outcomes.

020 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 30/12/2024

*** Except when clinically indicated 😌 Kidding. I’ll check my fridge when I get home, I’m curious now.

110 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 30/12/2024

* For legal reasons this is a joke, and antibiotics are great when used appropriately! 😝

020 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 14/12/2024

Adding mine in 😄 happy Caturday from Wheatley and Dewey!

151 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 30/11/2024

Agree! All our med students heavily rely on Sketchy. I haven’t dug into it yet – but I will since all of them do!

030 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 30/11/2024

For sure, she fit it in perfectly for those in-between moments. Planning to order my set soon!

120 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 30/11/2024

Honestly, @empiricgame.bsky.social’s card set was great to learn some of the antibiotics. My ID preceptor (back when I was training) @ashpergillus.bsky.social played with me during my rotation and I learned a ton. Planning to implement it for my students 😝

140 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 23/11/2024

Eep, a bit scary. Not for us since we use carbapenems as our B-lactams anyway, but I’ve been OK with TZP in uncomplicated urinary ESBL infections in the past.

110 0

Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/11/2024

🔥Everyone's favorite #shorterisbetter table is updated🔥 "BALANCE is now published, so the table is now updated! GNB bacteremia is now listed as Bacteremia(non S.aureus) Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg #idsky

03212 0

Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · 18/11/2024

Happy 🟪 Antibiotic Awareness Week 🟪 Along with presentations, we will be raffling off microbe pins, keychains, and gift cards! What are you doing for #USAAW24? #IDSky #MedSky

25710 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 18/11/2024

I feel like this has to be how ibrexafungerp was named

110 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 18/11/2024

Happy World Antimicrobial Awareness Week #WAAW! In honor of WAAW, I wanted to do a quick word unscramble of some of our common antibiotics 💊 Can you guess them?

150 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 18/11/2024

Always love that this is a global event 🦠🌎

020 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 17/11/2024

Interesting! We don’t report it out like that, so luckily one less thing to worry about. I’m also team CRO but only for my personal notes since it can be taken as so many other things.

000 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 17/11/2024

Right. I was explaining this to my PGY-1 I have on with me this month and I got her excited about the brand name, too. 😝

010 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 16/11/2024

Let’s talk about cefiderocol 💊 everyone’s favorite mechanism of entry #IDSky #AMSSky #PharmSky

5293 0

Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 16/11/2024

🆕️⚡️ ⚡️ #ofid Implementing oral antibiotics for bone and joint infections: Lessons learned and opportunities for improvement #idsky academic.oup.com/ofid/article... academic.oup.com/ofid/advance...

academic.oup.com

Implementing oral antibiotics for bone and joint infections: Lessons learned and opportunities for improvement

AbstractBackground. Although intravenous antibiotics have historically been the standard of care for bone and joint infections, clinical trial data has hig

23410 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 16/11/2024

Oh, this is beautiful. Especially love the TTE vs TEE + AMP/CRO synergy visuals. And definitely stealing that drug table 👀

020 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 16/11/2024

Always so excited to get more data in the penicillin allergy realm 💊

010 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 16/11/2024

Seems like this case was someone on prolonged B-lactam therapy. I don’t think susceptibilities are something that need to be done routinely quite yet – maybe if it becomes a trend. What are your thoughts?

120 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 16/11/2024

Not a block I wanted to fill on my 2024 ID bingo card.

010 0

Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Alice Han @dralicehan.bsky.social · 15/11/2024

#IDsky Today I did a panel discussion at Rush for medical students interested in going into ID. It was so fun to see young folks interested in ID! We need to plant the seeds early. This is a nice article on how to communicate how wonderful our field is 👇 doi.org/10.1093/ofid...

doi.org

Shaping the Future of Infectious Diseases: The Journey to Promote Value, Opportunity, and Positive Messaging

Abstract. The field of infectious diseases (ID) offers a rewarding career path and is widely viewed as an essential subspecialty in medicine. However, in r

3297 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 15/11/2024

Honestly I enjoy just browsing EUCAST's ECOFF database. 😆

120 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 15/11/2024

What are your favorite epidemiological cutoff value pearls? #IDSky 🧫

1113 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 14/11/2024

So neat to me! We use cefepime all day every day. Do you use ceftazidime instead as your antipseudomonal cephalosporin?

200 0

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · 14/11/2024

Ha – for sure! It’s such a great article. 2005 and still a great overview today for the Class As!

020 0