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Athanasios Oikonomou

@aoikonomou.bsky.social
5 followers 7 following 0 posts

Postdoc - Human Technopole

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Reposted by Athanasios Oikonomou
ifernandezrebollo.bsky.social @ifernandezrebollo.bsky.social · 30/06/2026
Excited to share our new bioRxiv preprint! We present GepiClock, an epigenetic clock trained on cancer methylomes predicting age in both cancer and normal samples outperforming previous clocks. Applied to cancer cell lines, it reveals age-linked gene dependencies and drug response vulnerabilities.
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Reposted by Athanasios Oikonomou
ifernandezrebollo.bsky.social @ifernandezrebollo.bsky.social · 30/06/2026
www.biorxiv.org/content/10.6...
biorxiv.org
A Generalised Epigenetic Clock Reveals Therapeutic Vulnerabilities Linked to Ageing in Cancer Cells
Epigenetic clocks estimate biological age from DNA methylation patterns but perform poorly in cancer due to extensive epigenetic reprogramming, limiting the study of ageing in tumour biology. Here, we...
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Reposted by Athanasios Oikonomou
ifernandezrebollo.bsky.social @ifernandezrebollo.bsky.social · 30/06/2026
Huge thanks to my co-first author @alessandrodigilio.bsky.social. I’m also very grateful to @aoikonomou.bsky.social, my supervisor @francescoiorio.bsky.social and @ioriolab.bsky.social from @humantechnopole.bsky.social, and @manelesteller.bsky.social for their guidance and support.
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