Reposted by Anu Sharma
Our newest preprint is out! 🧫
Can pathogens affect epithelial regeneration? And if so, what are the consequences for the tissue and pathogen physiology?
We used pyocyanin, a Pseudomonas aeruginosa metabolite, to start addressing this.
www.biorxiv.org/content/10.64898/2026.06.15.732350v1 🧵
biorxiv.org
Pyocyanin disrupts airway regeneration to favor chronic Pseudomonas aeruginosa infection
During chronic infections, host tissues undergo repeated cycles of injury and repair while being exposed to bacterial products. Although many virulence factors trigger immune responses, whether bacter...