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Anna Bodzeta

@annabodzeta.bsky.social
67 followers 84 following 11 posts

Microscopy, neuroscience, biophysics Postdoc in Grieve lab, School of Biochemistry, University of Bristol

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Reposted by Anna Bodzeta
adam grieve @adamgrieve.bsky.social · 17/09/2026
What if a membrane protein’s movement is as important as what it does? Our latest work reveals the unrestricted lateral mobility of a rhomboid protease enables neuronal synapse remodelling tinyurl.com/yk6xfxzr All credit to @annabodzeta.bsky.social for this stunning work, who is on the job hunt!
A cartoon depicting the unhindered movement of the rhomboid protease RHBDL2, which is required for it to encounter available synaptic adhesion proteins. Without this process, excitatory synapses fail to remodel.
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Anna Bodzeta @annabodzeta.bsky.social · 17/09/2026
Here it is my 1st preprint about synapse and rhomboid intramembrane protease: www.biorxiv.org/content/10.6... Using imaging and biochemistry, together with @adamgrieve.bsky.social we identify RHBDL2 as a membrane-immersed regulator of synapses architecture. 1/2
biorxiv.org
The unhindered lateral mobility of a rhomboid intramembrane protease enables synapse remodelling
Synapses must maintain their stable molecular organisation while retaining the capacity to remodel in response to changing demands. In order to flexibly change synaptic strength, the abundance of tran...
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Reposted by Anna Bodzeta
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 16/09/2026
The unhindered lateral mobility of a rhomboid intramembrane protease enables synapse remodelling www.biorxiv.org/content/10.64898/20…
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Anna Bodzeta @annabodzeta.bsky.social · 11/09/2026
While waiting for the manuscript to be uploaded on bioRxiv, here some sneak peek #FluorescenceFriday
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Anna Bodzeta @annabodzeta.bsky.social · 03/07/2026
#Neurons are amazing! #Actin is amazing! #FluorescenceFriday
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Anna Bodzeta @annabodzeta.bsky.social · 22/05/2026
One microscope to rule them all
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Anna Bodzeta @annabodzeta.bsky.social · 18/05/2026
One of the best, most inspiring imaging conference I've ever attended. Great science, great scientists, great location and great ... food. Big thanks to all people involved.
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Reposted by Anna Bodzeta
bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 28/03/2026
Kinase-gated coincidence detection controls kinesin-driven lysosome transport www.biorxiv.org/content/10.64898/20…
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Reposted by Anna Bodzeta
Kirsty McMillan @mcmillanlab.bsky.social · 06/02/2026
Exciting conference alert! The 93rd Biochemical Society Harden Conference will be on "Endosomal-lysosomal network dysfunction in neurodegeneration" on the South coast of England (1st to 4th of September 2026). Lots of speaker slots available from submitted abstracts so do come and join us!
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Reposted by Anna Bodzeta
adam grieve @adamgrieve.bsky.social · 25/11/2025
Add our first pre-print to your reading list? Using AF2 and MD, we've characterised structures and conformational ensembles of human rhomboid proteases - and revealed some surprises along the way. Feel v.lucky to work alongside Bryony & @robincorey.bsky.social! Please share: tinyurl.com/3h8r7f5y
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Anna Bodzeta @annabodzeta.bsky.social · 30/04/2025
''Understanding how techniques work is essential to getting good images in the first place.'' 100% agree.
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Anna Bodzeta @annabodzeta.bsky.social · 10/04/2025
Come and join us in solving mystery of plasma membrane proteostasis in beautiful neurons.
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