iiinova — where your digital self keeps evolving

Anke Sparmann

@ankesparmann.bsky.social

Scientific writer @helmholtz-hiri.bsky.social and editor at Life Science Editors (www.lifescienceeditors.com)

Anke Sparmann @ankesparmann.bsky.social · 12/09/2025

2/2 @jorg-vogel-lab.bsky.social, @gerovac.bsky.social & team @helmholtz-hiri.bsky.social developed a non-genetic antisense oligomer approach to silence phage genes and probe their function—a powerful tool for functional genomics & phage therapy. Now out @nature.com go.nature.com/46b1XAQ

Cartoon depiction of the antisense oligomer approach to silence transcripts from phages in infected bacteria. In the top left, a bacteriophage infects a bacterial cells and injects its DNA, which is transcribed into an mRNA and expressed into a protein. In the top right, antisense oligomers (shown in red) delivered into the bacterium bind to the target phage mRNA and prevent synthesis of the phage protein. If the encoded protein is essential, phage replication and bacterial cell lysis (shown on the bottom right) are halted and the bacterium is protected, depicted by a red shield (bottom left).

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Anke Sparmann @ankesparmann.bsky.social · 05/02/2025

Spring - could this be you?

Winter aconites in the sun, grass and dried leaves in the background

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Anke Sparmann @ankesparmann.bsky.social · 03/02/2025

The American Society for Microbiology (ASM) has apparently taken down web content related to Diversity, Equity and Inclusion (DEI) as they "evaluate the new Executive Orders."

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