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Andreas H. Laustsen-Kiel

@andreaslaustsen.bsky.social
105 followers 28 following 90 posts

Professor & Biotech Entrepreneur Antibody discovery | Toxinology | Snakebite envenoming | Infectious diseases | Microbiome | Antimicrobial resistance Website: antibody.dk

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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 09/06/2026
4-year postdoc position available in my lab. Come work with toxins and antibodies, and help us do some cool protein science using both in vitro and in silico methods: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
efzu.fa.em2.oraclecloud.com
Postdoc in environment-responsive antibody and nanobody discovery - DTU Bioengineering
Join an interdisciplinary team developing precision molecular tools to control protein function using advanced experimental and computational methods.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 29/04/2026
New paper from the lab, where we demonstrate a new approach for producing #snakebite #antivenom using recombinant #nanobodies and low-cost microbial #biomanufacturing, out in Trends in Biotechnology. Read paper here: www.sciencedirect.com/science/arti...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 28/04/2026
New paper from the lab, where we demonstrate a new approach for detecting #toxins from #cholera and E. coli using point of care #diagnostic principles. Read paper here: pubs.rsc.org/en/content/a...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 01/04/2026
New research article from the lab on direct #protein #sequencing without genomic references, which is (normally) particularly challenging: www.mcponline.org/article/S153... Thanks to great co-authors and generous funders!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 01/04/2026
New review from the lab on large animal models used for studying #snakebite #envenoming and evaluating #therapeutic interventions: www.nature.com/articles/s44...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 06/03/2026
Excited to share our new study showing how combining consensus #allergens with intracellular delivery via #mRNA-LNP technology could help treat #allergy: www.nature.com/articles/s41... Led by Esperanza Rivera de Torre and a fantastic international team across academia and industry!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 21/02/2026
To those interested in watching my dr.techn. (higher doctorate) defense on #Engineering #Antivenom, but did not get the chance to see it live, here is the full lecture and Q&A: www.youtube.com/watch?v=xWA_...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 15/01/2026
Job opening in Y-king Biologics! We are looking for a Senior Scientist to help us develop pH-responsive antibodies for therapeutic purposes: bioinnovation-ac23af.careers.hibob.com/jobs/58efb9a... Y-king Biologics is a Bio Studio project at the BioInnovation Institute: bii.dk/community/st...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 09/01/2026
Thanks to Blake Forman for highlighting snakebite as a neglected tropical disease and my group’s research efforts towards developing better antivenoms: www.technologynetworks.com/biopharma/ar...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 06/01/2026
Exalted to announce that Bactolife has just secured over EUR 30 million from new and existing investors to commercialise and clinically validate our binding proteins! Press release: www.bactolife.com/bactolife-se...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/12/2025
New paper from the lab on how #virulence of human #pathogenic enterotoxigenic E. coli and V. cholerae can be attenuated using #binding #proteins: www.tandfonline.com/doi/full/10.... Thanks to great co-authors and funders!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 15/12/2025
For those that are interested, I am defending my dr.techn. dissertation (Engineering antivenom) on January the 23rd at 9.00-12.00 CET in meeting room 1 (first floor) at the Technical University of Denmark: dtu.dk/kalender/dok...
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Reposted by Andreas H. Laustsen-Kiel
Genome Biology and Evolution @genomebiolevol.bsky.social · 09/12/2025
Rao, @andreaslaustsen.bsky.social et al. present a chromosome-level genome assembly of the western nose-horned viper. The 1.55 Gbp assembly (contig N50 = 45.9 Mb; scaffold N50 = 210 Mb; BUSCO = 97.1%) is anchored into 18 pseudo-chromosomes. 🔗 doi.org/10.1093/gbe/evaf210 #genome #evolution
GBE | A Chromosome-level Genome Assembly of the Western Nose-Horned Viper (Vipera ammodytes ammodytes)

The photo shows western nose-horned viper (Vipera ammodytes ammodytes) in the wilds of Slovenia. Photo by Griša Planinc.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 27/11/2025
Excited to announce that my dr.techn. (higher doctorate) dissertation #Engineering #Antivenom is now accepted for defence at the Technical University of Denmark and publicly available: orbit.dtu.dk/en/publicati...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 24/11/2025
...from University of Reading, Technical University of Denmark, and Universidad de Costa Rica. Also, a big thanks to our funders, Villum Foundation, European Research Council, Wellcome, Medical Research Council, Marie Skłodowska-Curie Actions, and to Trends in Biotechnology for publishing the work!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 24/11/2025
Thanks to my fantastic collaborators, José R. Almeida, Christoffer Vinther Sørensen, Soheil Gilabadi, Jarred Williams, Husain Bin Haidar, Mark von Bülow Møiniche, Melisa Benard Valle, Esperanza Rivera de Torre, David Schultz, Andrew Urquhart, Bruno Lomonte, Ketan Patel, and Sakthivel Vaiyapuri...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 24/11/2025
Can #mRNA technology be used to treat #snakebite #envenoming? In this new paper, we explore the utility of mRNA-encoded #antibodies delivered using lipid nanoparticles to neutralise #snake #toxins. Read paper: www.sciencedirect.com/science/arti...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 20/11/2025
For the Danish speaking audience, @videnskab.dk has made a portrait of me and my research career so far, focusing mostly on my work on snakebite envenoming, but also a few other projects, including research done at Bactolife and VenomAid Diagnostics: videnskab.dk/naturvidensk...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 20/11/2025
Fantastic to see our article "Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites" on the cover of @nature.com, represented by a beautiful picture of the Eastern green mamba, taken by Prof. Wolfgang Wüster! Read article here: www.nature.com/articles/s41...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 11/11/2025
New paper from the lab, where we sequenced the genome of Europe's most venomous snake, Western nose-horned viper (Vipera ammodytes ammodytes)! Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 04/11/2025
We use very small doses. Enough to activate the immune system, but not so much that they harm the animals.
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Reposted by Andreas H. Laustsen-Kiel
Christie Wilcox @nerdychristie.bsky.social · 30/10/2025
While a new, broad-spectrum 'nanobody' antivenom performed impressively in preclinical trials, the real significance is “showing this is possible,” @andreaslaustsen.bsky.social told me. That and more of the best from @science.org and science in #ScienceAdviser: www.science.org/content/arti... 🧪
Synthetic mix of “nanobodies” protected mice from lethal doses of venom from 17 of 18 African snakes—all except the eastern green mamba (Dendroaspis angusticeps). CREDIT: Wolfgang Wüster
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Reposted by Andreas H. Laustsen-Kiel
Menzies Lab @menzieslab.bsky.social · 30/10/2025
Excited to share a new paper led by @andreaslaustsen.bsky.social, Anne Ljungars, @tpjenkins.bsky.social, Shirin Ahmadi and Nick Burlet. It was a privelege to be a part of this amazing team! www.nature.com/articles/s41...
nature.com
Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites - Nature
A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkha...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 29/10/2025
New article from the lab, where we describe how we developed a "Nanobody-based recombinant #antivenom for #cobra, #mamba, and #rinkhals bites" out in @nature.com!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 22/10/2025
New review article from the lab on "Advances in #antibody-based strategies for targeting #cancer-associated #glycopeptide antigens" just out in Drug Discovery Today, mainly written by my awesome PhD student, Edward Meier! Read paper: sciencedirect.com/science/arti...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 11/10/2025
For those understanding German that are interested in getting up to date with the world of #snakebite #antivenoms and research in this field, Brigitte Osterath has written a great article for @gdch.de: gdch.app/article/wenn... Full access: www.writingscience.de/artikel/schl...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 12/09/2025
This opens a path to acid-switched / sweeping antibodies that recycle and neutralise multiple antigens without changing the paratope. #sweeping #toxins #mAbs #acidswitching Thanks to all co-authors & funders for making this possible!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 12/09/2025
I’m excited to share our new paper in mAbs! We engineered pH-dependent antibodies without histidine “doping,” showing the light chain controls pH sensitivity by modulating water access. Link: www.tandfonline.com/doi/full/10....
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
Also a big thanks to our generous funders, Villum Fonden, European Research Council (ERC), Wellcome Trust, and Consejo Nacional de Ciencia y Tecnología!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
Johannes R. Loeffler, Andrew B. Ward, Kim Boddum, Jens Preben Morth, and Esperanza Rivera de Torre from @dtu.dk, Universidad Nacional Autónoma de México, Sophion Bioscience, and Scripps Research.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
Thanks to great co-authors, including Anna Damsbo Jensen, Nick J. Burlet, Monica L. Fernández-Quintero, Melisa Benard-Valle, Max Overath, Alid Guadarrama-Martínez, Anneline Vlamynck, Ida Bisbo, César Noé Villalobos Carrizosa, Tulika Laprade, Alejandro Alagon...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
While the work has immediate implications for snakebite envenoming, the methodologies developed here are generally useful for developing broadly-neutralising antibodies.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
Read article here: www.nature.com/articles/s42...
nature.com
Structural mechanisms behind the neutralisation of long-chain α-neurotoxins by broadly neutralising VHHs discovered using a consensus antigen - Communications Chemistry
Snakebite envenoming remains a critical global health issue due to the diverse antigenic profiles of snake venoms. Here, the authors develop a long-chain consensus α-neurotoxin to identify broadly neu...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 19/07/2025
Excited to share the newest research paper from our lab, where we discover #nanobodies against #snake #neurotoxins using specially designed #consensus toxins and phage display technology. Link to paper in first comment.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 29/06/2025
Thanks also to our generous funders, Villum Fonden, European Research Council, Wellcome Trust, and Consejo Nacional de Ciencia y Tecnología!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 29/06/2025
Thanks to my fantastic co-authors, Anna Damsbo Jensen, Melisa Benard-Valle, Tom Jansen, Nick J. Burlet, Max Overath, Alid Guadarrama-Martínez, Kim Boddum, Alejandro Alagon, and Esperanza Rivera de Torre from DTU, UNAM, and Sophion Biosciences. .
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 29/06/2025
New research article where we use consensus #toxins as #antigens for discovery of #nanobodies, showcasing this with short-chain alpha-neurotoxins from snakes - notoriously difficult to discover antibodies against. Read article here:https://www.tandfonline.com/doi/full/10.1080/19420862.2025.2522838
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 11/06/2025
Thanks to Laura Tran for highlighting our work on Binding Proteins against cholera toxin: www.the-scientist.com/new-cholera-... Original research article: www.nature.com/articles/s41...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 05/06/2025
Happy to share this "Ubegribeligt" podcast episode (in Danish) on venom and antivenom, which I had the pleasure of doing together with Huxi Bach from Danmarks Radio: www.dr.dk/lyd/p1/ubegr... In the podcast, we discuss animal venoms, antivenom, and R&D, and spinout!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 02/06/2025
... Sandra Wingaard Thrane & Nuria Canibe. Thanks to GUDP - Grønt Udviklings- & Demonstrationsprogram for the financial support to make this happen!
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 02/06/2025
The work was done by researchers from Bactolife, Aarhus University, Technical University of Denmark, and Università degli Studi di Parma, including Jiajia Xu, Melania Andrani, Rikke Brødsgaard Kjærup, Tina Sørensen Dalgaard, Carsten Eriksen, Susanne Brix Pedersen...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 02/06/2025
The Binding Proteins developed here retain full functionality when subjected to the very harsh process of pelleting, as part of admixing them into piglet feed, as can be seen in the figure.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 02/06/2025
Pleased to share this new publication on the effects of Binding Proteins against virulence factors from enterotoxigenic E. coli: jasbsci.biomedcentral.com/articles/10.... As an #antibody engineer, I find it super interesting that we in this study show how stable #Binding #Proteins can be!
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Reposted by Andreas H. Laustsen-Kiel
Timothy P. Jenkins @tpjenkins.bsky.social · 14/05/2025
🚨 We’re hiring a PhD student! 🚨 Join us at DTU Bioengineering + collaborators Messoud & Håkan Ashina + Esperanza Rivera de Torre to bring preventative migraine therapeutics from 💻 to 🧠 🔗 Apply: lnkd.in/dCRU_EN3 🔍 Project: lnkd.in/dbpi8MwX
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Reposted by Andreas H. Laustsen-Kiel
Anton Autzen @aaaautzen.bsky.social · 11/05/2025
I co-wrote an opinion piece in a Danish newspaper. There are a few EU initiatives focused on recruiting american scientist. These ignore that the developments in the US the past years have spread here as well. We need a strategy and stronger political will, if we are to be a safe haven for science.
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Reposted by Andreas H. Laustsen-Kiel
Timothy P. Jenkins @tpjenkins.bsky.social · 12/05/2025
🚨 Big news! We’ve received a NovoNordisk Foundation Tandem Grant for #MIGRAINE — designing #AI-powered #GPCR-targeting biologics for chronic migraine. From computer to human in 4 years. Proud to team up with Messoud and Hakan Ashina, as well as Esperanza Rivera de Torre! 🧠 + 💊 + 🧬 = new hope.
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 06/05/2025
Read more about the companies: tropicalpharmacology.com/entrepreneur... These include: Bactolife, VenomAid Diagnostics, Chromologics, Biosyntia, Antag Therapeutics, VenomAb, Combotope Therapeutics ApS, Agrobiomics, and soon-to-be-a-company Y-kings (bii.dk/bio-studio-p...)
tropicalpharmacology.com
Entrepreneurship | Center for Antibody Technologies
In the Center for Antibody Technologies, we strive to use scientific research to solve problems […]
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 06/05/2025
DTU has a large number of excellent and innovative researchers, and each year more than 100 companies are spun out of the university, so receiving this award is very humbling.
tropicalpharmacology.com
Entrepreneurship | Center for Antibody Technologies
In the Center for Antibody Technologies, we strive to use scientific research to solve problems […]
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 06/05/2025
I am grateful to the Technical University of Denmark (DTU) who kindly awarded me with the university's Innovation Award 2025 for my contributions to innovation, entrepreneurship, and spinout of companies. www.dtu.dk/nyheder/alle...
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Andreas H. Laustsen-Kiel @andreaslaustsen.bsky.social · 03/05/2025
I shared thoughts with @statnews.com on new research aiming to develop a universal antivenom, using antibodies from Tim Friede’s decades of self-immunization. Thanks to @usha.bsky.social for including me in the scientific discussion. 🐍👇 www.statnews.com/2025/05/02/d...
statnews.com
Snake enthusiast survived hundreds of bites. Now his blood is aiding the search for a universal antivenom
Blood from a snake enthusiast who's been bitten hundreds of times aided the search for a universal snakebite treatment
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