Reposted by Andreas Fellas
Our latest Preprint is now on BioRXiv: www.biorxiv.org/content/10.1...
It explains how heterochromatin-dependent epimutations mediate resistance to caffeine & antifungals by imposing mitochondrial dysfunction.
Thanks to all authors for their efforts especially Andreas Fellas & Alison Pidoux. Enjoy!
biorxiv.org
Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance
Global health and food supply are endangered by an increasing frequency of antifungal resistance in pathogenic fungi. Wild-type fission yeast, Schizosaccharomyces pombe, can gain resistance to insults...