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Reposted by RossiLab

Alessandro Prigione @aleprigio.bsky.social · 27/05/2026

Fantastic work from @andrearossilab.bsky.social Rossi lab on the development of @cleanfinder.bsky.social for nuclear and mitochondrial genome editing application. Greatful that my lab have contributed!

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RossiLab @andrearossilab.bsky.social · 22/05/2026

Excited to share that our work on CleanFinder is published in Trends in Biotechnology! 🎉 Analyzing complex allele mixtures across editing modalities and sequencing platforms is a major bottleneck. We developed CleanFinder to solve this. Read it here: www.sciencedirect.com/science/arti...

sciencedirect.com

CleanFinder: a scalable framework for comprehensive genome editing analysis

Genome editing often generates complex mixtures of alleles rather than single, predefined outcomes. Resolving these heterogeneous edits across diverse…

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RossiLab @andrearossilab.bsky.social · 25/03/2026

Great to see our work published in CELL Using patient-derived iPSCs and organoids, we identified PDE5 inhibitors as candidates for Leigh syndrome Early patient data support clinical translation. Congrats to the team, especially Alessandro Prigione 🔗 tinyurl.com/2sbfk463 #StemCells #Mitochondria

tinyurl.com

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leig…

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