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Ana Dopico-Fernandez

@anadopico.bsky.social
45 followers 99 following 0 posts

PhD student at the MRC Weatherall Institute of Molecular Medicine (University of Oxford). Interested in chromatin and transcription regulation.

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Reposted by Ana Dopico-Fernandez
MRC Weatherall Institute of Molecular Medicine @imm.ox.ac.uk · 05/03/2026
#WIMMReads 🧪 From the Thomas Milne, Robert Beagrie and James Davies Groups: FACT is identified as a key regulator of 3D genome organisation, helping preserve promoter topology and large scale chromatin structure. Read more👇 #GenomeBiology #Chromatin #WIMM @rdm.ox.ac.uk @medsci.ox.ac.uk #AcademicSky
doi.org
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Reposted by Ana Dopico-Fernandez
Rob Beagrie @rbeagrie.bsky.social · 19/02/2026
New preprint from @anadopico.bsky.social (who I have had the great pleasure of supervising with Tom Milne) and our fantastic collaborators in the @davieslab.bsky.social www.biorxiv.org/content/10.6... #genomics #GeneRegulation #chromatin
A pictographic model of chromatin folding in the nucleus. DNA wrapped around nucleosomes aggregates into nanoscale domains, whilst newly nucleosome depleted DNA that forms after acute degradation of FACT projects from these domains and engages in long-range interactions that can span TAD boundaries
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