Happy to announce our preprint going live on BioRxiv! Interested in what’s happening to your fibroblasts’ transcriptomic phenotype once it’s in culture? Look no further!
www.biorxiv.org/content/10.1...
@denklab.bsky.social
#fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal
biorxiv.org
Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features
In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...