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Amy Lock

@amy-lock.bsky.social
88 followers 132 following 4 posts

Postdoctoral researcher in Denk lab and Shaw lab. Researching aberrant sensations in keloid scars. stromal cells | single cell sequencing | iPSC sensory neurons | clinical & translational | pain & itch

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Amy Lock @amy-lock.bsky.social · 20/08/2025
Happy to announce our preprint going live on BioRxiv! Interested in what’s happening to your fibroblasts’ transcriptomic phenotype once it’s in culture? Look no further! www.biorxiv.org/content/10.1... @denklab.bsky.social #fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal
biorxiv.org
Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features
In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...
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Amy Lock @amy-lock.bsky.social · 18/04/2025
Hi everyone! I’m seeking a new role and would appreciate your support. If you hear of any opportunities, please send me a message! #OpenToWork About me: 💼 I’m looking for Postdoctoral/Senior Scientist roles. 🌍 London. ⭐ currently work in fibrosis/scarring/pain/itch ⏰ previously worked in biotech
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Amy Lock @amy-lock.bsky.social · 07/03/2025
#FluorescenceFriday testing an ATF3 antibody on newly replated immature iPSC-derived sensory neurons. Never get bored of these beautiful images 😍 @denklab.bsky.social
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Amy Lock @amy-lock.bsky.social · 24/01/2025
#FluorescenceFriday finally got some keloid scar sections to beautifully show their stromal and sensory neuron architecture! Green = FAP (fibroblasts), white = CD31 (endothelial cells), red = b3-tubulin, blue = DAPI. @denklab.bsky.social
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