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ameachasag.bsky.social

@ameachasag.bsky.social

Reposted by @ameachasag.bsky.social

Francesca Ciccarelli @ciccarellilab.bsky.social · 19/02/2025

We have two open positions for #computationalbiologists to work on: 1. Early cancer initiation following our work in #NatureCancer (Ref 5028) 2. Response to cancer immunotherapy following our work in #CancerCell (Ref 5073) To apply use the provided reference numbers: www.qmul.ac.uk/jobs/vacanci...

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Reposted by @ameachasag.bsky.social

Francesca Ciccarelli @ciccarellilab.bsky.social · 03/01/2025

Best start of 2025: our study on the dual role of CDKN2A in cancer evolution (rdcu.be/d5pty) is out in @naturecancer.bsky.social! Big thanks to Piyali Ganguli who led it, all coauthors and @cancerresearchuk.org archuk.org @crick.ac.uk @qmbci.bsky.social bci.bsky.social for support! Summary below

rdcu.be

Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer

Nature Cancer - Ganguli et al. show that CDKN2A loss in Barrett’s esophagus prevents esophageal adenocarcinoma initiation by counterselecting subsequent TP53 loss and report context-dependent...

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