iiinova — where your digital self keeps evolving

Amber Luckett

@ambermluckett.bsky.social

18 followers 20 following 3 posts

Postdoc researching Type 1 Diabetes genetics @ University of Exeter 🧬🌊

Posts Replies Media

Amber Luckett @ambermluckett.bsky.social · 10/09/2026

I am very excited to share our latest paper on type 1 diabetes genetics has been published in Diabetologia! 🧬 A big thanks to all my co-authors for their collaboration and support on this project! #Type1Diabetes #Genetics #GWAS #Diabetologia #Research #PrecisionMedicine

052

Amber Luckett @ambermluckett.bsky.social · 18/08/2025

Our new preprint is now available on medRxiv! 🎉 Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D 🔗 tinyurl.com/3fr2kcny A huge thank you to all involved!🧬 #type1diabetes #genetics #type1diabetesresearch #preprint

medrxiv.org

Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D

Background There are substantial differences in the clinical presentation of type 1 diabetes (T1D) depending on the first-developing autoantibody, although the underlying mechanisms are poorly underst...

000

Reposted by Amber Luckett

Luke Jostins-Dean @lukejostins.bsky.social · 24/05/2025

Interesting finding from @ambermluckett.bsky.social - the non-HLA GWAS of HLA DR3+ and DR4+ type 1 diabetes are surprisingly different (coheritability is only 0.68). Some evidence of less adaptive (CD4) and more innate (mast cell) enrichment in DR3 genetics. #eshg2025

011

Reposted by Amber Luckett

Dr Gareth Hawkes @drghawkes.bsky.social · 23/05/2025

Got a big showing of talented University of Exeter scientists with talks and posters at ESHG25 in Milan. Come along and find out more! @hls.exeter.ac.uk @exeter.ac.uk #ESHG25 @jamesfasham.bsky.social @jingzhan.bsky.social @ambermluckett.bsky.social @chundru.bsky.social @harrygreentkd.bsky.social

0105

Amber Luckett @ambermluckett.bsky.social · 25/04/2025

Our new paper updating GRS2 with a new tool to easily generate standardised T1DGRS 🧬 Thanks to Seth Sharp, @annagloyn.bsky.social, Richard Oram and @mnweedon.bsky.social for a great collaboration! tinyurl.com/4bsaz9hx

tinyurl.com

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts

Amber M. Luckett, Richard A. Oram, Aaron J. Deutsch, Hector I. Ortega, Diane P. Fraser, Kaavya Ashok, Alisa K. Manning, Josep M. Mercader, Manuel A. Rivas,

022