We report a case of anaphylactic shock in an O patient transfused with a B platelet unit. The in vitro data suggest, but do not prove, that the reaction was mediated by recipient alpha-gal IgE. Furthe...

The lone star tick ( Amblyomma americanum Linnaeus) is a species commonly found in the southeastern U.S., but in recent years its populations have expanded northward, resulting in an increased risk of...

<span><b>Background/Objectives:</b> This study investigates the potential of <i>Anisakis</i> sp. as a novel source of α-Gal (Galα1-3Galβ1-4GlcNAc-R) epitopes capable of inducing allergic sensitization...

Abbreviations: AGS (alpha-gal syndrome), IgE (immunoglobulin E), ICD (International Classification of Diseases), HRSA (Health Resources and Services Administration)

We demonstrate a substantial incidence of adverse drug reactions and presumed anaphylaxis to crotaline antivenoms in an α-GAL endemic region, with F(ab')₂ antivenom associated with more rea...

Hypersensitivity reactions (HSRs) limit cetuximab use in KRAS wildtype advanced colorectal cancer, with a significant driver being pre-formed IgE antibodies against galactose-1,3-alpha-galactose (alph...

Allergic reactions in response to arthropod bites are a growing concern worldwide. Alpha-Gal syndrome (AGS) is a red meat allergy associated with IgE antibodies against galactose-alpha-1,3-galactos...

Evidence supporting the possibility of a new adverse event, TRAGS, is accumulating. This study quantifies how often Group O patients may be exposed to Group B antigen in Group B or AB plasma and/or pl...

Alpha-gal syndrome (AGS) was first described by Commins and Platts-Mills in 2009 as an IgE-mediated allergic reaction to galactose-alpha-1,3-galactose (alpha-gal) residues on nonprimate mammalian tiss...

Alpha-gal syndrome presenting in the emergency department: a case report

The α-gal syndrome (AGS) is a food allergy towards galactose‐α‐1,3‐galactose (α‐gal) present in mammalian meat and it usually develops after tick bite…

We report a case of a 40-year-old male who presented with sensation of throat closing and shortness of breath while at work at a meat processing facility. The differential diagnosis of shortness of br...

Decellularization does not completely remove the matrix-bound α-Gal epitopes in porcine acellular dermal matrix (pADM), and the presence of residual α-Gal epitopes could elicit adverse immunological r...

This study provides valuable insights that should be considered to improve TBDs surveillance and diagnostic strategies, as well as developing preventive measures to reduce tick bite exposure and TBD c...

The alpha-Gal syndrome (AGS) is an underdiagnosed tick-borne allergy characterized by both immediate and delayed IgE-mediated anaphylactic reactions to the galactose-alpha-1,3-galactose (alpha-Gal) ep...