iiinova — where your digital self keeps evolving

Reposted by Alessandro Dulja

Oded Rechavi @odedrechavi.bsky.social · 29/09/2026

Mark your calendar! So excited to organize “Frozen Accidents” with art historian Sefy Hendler! Join us Nov 20th at Galerie Colbert (INHA), Paris. Hosted by HiCSA, Paris 1 Panthéon-Sorbonne. Please share widely, especially outside your field. Be there or be frozen!!! (see poster & thread for details)

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Reposted by Alessandro Dulja

EMBL @embl.org · 31/07/2026

Imagine a tool that lets you test-drive gene expression inside a living cell. EMBL researchers used a synthetic biology approach to test hundreds of DNA sequences for their effect on regulating gene expression in context. www.embl.org/news/science...

Illustration representing mCHIRA, a new method developed by the Krebs Group for this study, which allows scientists to insert regulatory DNA sequences into a specific section of the genome and test downstream effects inside the cell. Credit: Daniela Velasco/EMBL

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Reposted by Alessandro Dulja

Denis Duboule @denisduboule.bsky.social · 03/09/2025

‘Our Ancestors the Fish’, a course by Prof. @neilshubin.bsky.social, Univ of Chicago, invited Prof @college-de-france.fr. in Paris @psl-univ.bsky.social. Four conferences, free access, open to everyone, with Tiktaalik as a guest star. Friends, colleagues and fossils in Paris and around, please RT🥁

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Reposted by Alessandro Dulja

Babis Galouzis @babisgalouzis.bsky.social · 10/06/2025

Check our latest with Yacine Kherdjemil and @eileen-furlong.bsky.social and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression. www.cell.com/molecular-ce...

cell.com

Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation

Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions. Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during zygotic genome activati...

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Reposted by Alessandro Dulja

Valentina Baderna @valentinabaderna.bsky.social · 08/04/2025

Happy to share the latest story from @arnaudkr.bsky.social's lab @embl.org! With @guidobarzaghi.bsky.social, we used Single Molecule Footprinting to quantify how often chromatin is accessible at enhancers after TF and chromatin environment changes! Check our preprint bit.ly/3XQMFxN + thread ⬇️ 1/11

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