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Alberto Mazzoni @Sant'Anna Pisa

@albmazz.bsky.social
177 followers 77 following 36 posts

Computational Neuroengineer

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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 07/09/2026
L'ho trovata alla coop di via Carlo del Prete per esempio. Parte dei profitti va a una ONG Palestinese. Sull'Informatore trovi tutta la storia. Sicuro se vuoi aiutare Gaza ci sono modi più diretti. Ma sempre meglio che la Coca Cola.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 01/09/2026
Fabrizio de Andre Daft Punk Deftones Portishead Jane's Addiction Cure Radiohead Blur Beasts of bourbon Paolo Conte
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 28/08/2026
3) a livello associativo ci sono le comunità energetiche rinnovabili, si può agire a livello di posto di lavoro (efficientiamo e pannelliamo l'edificio etc). Se l'alternativa è questo mondo sempre meno vivibile mi pare valga la pena di impegnarsi un pò.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 28/08/2026
1) chiarire che voteremo in base alle misure di adattamento e mitigazione (diminuzione assoluta del consumo di combustibili fossili) messe in atto. Alle comunali alle regionali alle nazionali alle europee. 2) fare quel che possiamo a livello individuale (elettrificazione, abitudini alimentari etc)
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 22/08/2026
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 22/08/2026
Ma non c'è bisogno di dipendenza in senso stretto per indurre il tipo di comportamenti descritti molto bene nell'articolo. Basta una modulazione opportuna della dopamina. Mi occupo di neuroscienze della dopamina di professione. Consiglio la lettura del libro Dopamine Nation di Anna Lembke.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 19/08/2026
Bel libro e titolo fondamentale (che si applica in questo caso)
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 17/08/2026
Soundgarden De André Art Bakley
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 15/08/2026
Credevo CSI il gruppo musicale. Sarebbe stato decisamente meglio.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 05/08/2026
Al primo figlio/a dedichi il 30% del tempo, il 60% al lavoro il 10% allo svago. Dopo il secondo il lavoro rimane al 60% quindi dedichi ai tuoi figli 20% e 20%. Il primo figlio avverte la differenza e ti odia. Ti senti in colpa col secondo che riceve meno del primo. Non hai più tempo libero.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 04/08/2026
Lei aveva detto che non era possibile diminuire il consumo di fossili. Le ho dimostrato che è possibile. Visto che ogni emissione di co2 causa un aumento di temperatura e questo peggiora il nostro stato sulla terra mi sembra ovvio che se si può ridurre la co2 vada fatto. Chiudiamola qui.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 04/08/2026
Certo che è possibile e lo stiamo già facendo (vedi grafico allegato che è in termini assoluti) solo non abbastanza velocemente.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 04/08/2026
Come è possibile che neanche da questa estate scaturisca una coscienza della gravità del riscaldamento globale, della necessità di abbandonare totalmente e più velocemente possibile i combustibili fossili? Non mi voglio lamentare degli scemi, voglio capire come cambiare il discorso politico.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 04/08/2026
Predicting #Alzheimer's onset from EEG recordings thanks to a novel perspective on #DigitalTwins. A novel, non invasive, low cost prognostic method validated on 100s of patients thanks to the collaboration with Alzheimer Center Amsterdam. www.nature.com/articles/s41...
nature.com
Predicting Alzheimer progression using EEG-based digital twins - npj Digital Medicine
npj Digital Medicine - Predicting Alzheimer progression using EEG-based digital twins
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 31/07/2026
Infinite Jest. Non solo è un libro della vita, ma solo d'estate avrai abbastanza tempo per leggerlo
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Reposted by Alberto Mazzoni @Sant'Anna Pisa
John Bistline @bistline.bsky.social · 01/04/2026
This is my favorite climate change chart. Japanese monks, aristocrats, and emperors kept meticulous records of cherry blossom festivals for 1,200 years and accidentally built the world's longest climate dataset.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 09/03/2026
In Italy is quite common to take your bike on the train. There are two/three dedicated areas on each train. Plus, if you have a foldable bike you can place it in luggage areas. I have been doing this every working day in the last ten years, commuting between Pisa and Florence.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 20/02/2026
Interested in modeling #Parkinson’s therapies? Check out our model of the effects of Deep Brain Stimulation on basal ganglia dynamics. Just out in PLoS Comp Biol. journals.plos.org/ploscompbiol...
journals.plos.org
In silico model of basal ganglia deep brain stimulation in Parkinson’s disease captures range of effective parameters for pathological beta power suppression
Author summary Deep brain stimulation (DBS) is an effective treatment for alleviating symptoms of Parkinson’s disease (PD), but its underlying mechanism is unclear. Motor symptoms of PD are linked to ...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 01/02/2026
This is my first work with a potential impact on energy efficiency and hence on climate. Following neurons' example we can find alternatives to the madness of energy-hungry AI. My environmentalist side and my neuroscientific side are both happy.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 01/02/2026
Neuromorphic architectures do not simply learn to properly decode sensory stimuli: they do it in an energy efficient way. My latest work out in @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Bioinspired spiking architecture enables energy constrained touch encoding - Nature Communications
Current tactile sensing solutions face challenges in excessive wiring, high energy demands of AI computing, and limitations in scalability and parallel processing. Here, the authors present a neuromor...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 17/01/2026
Our personalized cortical models can diagnose #dementia early using non-invasive EEG/MEG. They generalize across data from different centers and recording modalities, boosting real-world reliability. #Neurotech #digital_twins www.nature.com/articles/s43...
nature.com
Digital twins support cross-modal and cross-centric classification of mild cognitive impairment - Communications Medicine
Amato et al. evaluate whether brain digital twins can be utilized to derive robust dementia biomarkers. Biomarkers derived from digital twin outperform standard MEG and EEG metrics in diagnosing patho...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 16/07/2025
aDBS revealed long-term drifts and sudden changes in #Parkinsons subthalamic activity. We propose a deep learning framework to predict them before they lead to clinical consequences www.nature.com/articles/s41...
nature.com
Transformer-based long-term predictor of subthalamic beta activity in Parkinson’s disease - npj Parkinson's Disease
npj Parkinson's Disease - Transformer-based long-term predictor of subthalamic beta activity in Parkinson’s disease
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 26/06/2025
No Italian more than six years old will consider it a carbonara. It's like confusing a wolf with a chihuahua.
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Reposted by Alberto Mazzoni @Sant'Anna Pisa
Eleonora Russo @russoel.bsky.social · 21/06/2025
Into population dynamics? Coming to #CNS2025 but not quite ready to head home? Come join us! at the Symposium on "Neural Population Dynamics and Latent Representations"! 🧠 📆 July 10th 📍 Scuola Superiore Sant’Anna, Pisa (and online) 👉 Free registration: neurobridge-tne.github.io #compneuro
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 13/06/2025
Per i lettori italiani, qui spiego come usiamo modelli matematici per la diagnosi dell' #Alzheimer in modo divulgativo www.lanazione.it/pisa/cronaca...
lanazione.it
Alleato contro l’Alzheimer. Un modello matematico per la diagnosi precoce
Sviluppato nei laboratori della Scuola Sant’Anna è capace di individuare con grande precisione l’insorgenza della malattia. Ne parliamo col suo creatore
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 13/06/2025
Novel work from the Computational Neuroengineering Laboratory at Sant'Anna (Pisa) From computational models to clinical applications: a digital twin of #Alzheimers enables prediction of individual patients' dementia evolution from non-invasive EEH recordings link.springer.com/article/10.1...
link.springer.com
Digital twins and non-invasive recordings enable early diagnosis of Alzheimer’s disease - Alzheimer's Research & Therapy
Background The diagnosis of Alzheimer’s disease (AD) in its preclinical stages, such as subjective cognitive decline (SCD), is crucial for a timely management of the condition. However, current early ...
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Reposted by Alberto Mazzoni @Sant'Anna Pisa
Nature @nature.com · 07/05/2025
Just over half of the children born in 2020 will face unprecedented exposure to heatwaves over their lifetime — even under a conservative projection for how climate change will unfold over the next 75 years go.nature.com/3YzbUFn
go.nature.com
How climate change will burden our children: data reveal a lifetime of extreme heat
Young people will be exposed to a number of heatwaves that no one would have experienced in pre-industrial times.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 05/04/2025
Our novel network model of early stages of #Alzheimer's identifies a phase transition in neurodegeneration parameters that could support early diagnosis based only on EEG recordings alzres.biomedcentral.com/articles/10....
alzres.biomedcentral.com
Personalized brain models link cognitive decline progression to underlying synaptic and connectivity degeneration - Alzheimer's Research & Therapy
Cognitive decline is a condition affecting almost one sixth of the elder population and is widely regarded as one of the first manifestations of Alzheimer’s disease. Despite the extensive body of know...
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Reposted by Alberto Mazzoni @Sant'Anna Pisa
CNN @cnn.com · 24/03/2025
The Palestinian co-director of Oscar-winning film "No Other Land" Hamdan Ballal was beaten up by Israeli settlers in the occupied West Bank and taken away by Israeli soldiers, his colleagues and eyewitnesses said.
cnn.com
Oscar-winning Palestinian director of ‘No Other Land’ assaulted by Israeli settlers in the West Bank | CNN
The Palestinian co-director of Oscar-winning film “No Other Land” Hamdan Ballal was beaten up by Israeli settlers in the occupied West Bank and taken away by Israeli soldiers, his colleagues and eyewi...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 11/03/2025
Don't forget to read the previous work about genetic profile and spiking patterns to have the complete picture onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Spiking Patterns in the Globus Pallidus Highlight Convergent Neural Dynamics across Diverse Genetic Dystonia Syndromes
Objective Genetic dystonia is a complex movement disorder with diverse clinical manifestations resulting from pathogenic mutations in associated genes. A recent paradigm shift emphasizes the functio...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 11/03/2025
Another piece of the puzzle of the genetic aetiology of dystonia falls into place: how the genetic profile affects spectral components of globus pallidus activity. onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Genetic Etiology Influences the Low‐Frequency Components of Globus Pallidus Internus Electrophysiology in Dystonia
Background Elevated low-frequency activity (4–12 Hz) within the globus pallidus internus (GPi) has been consistently associated with dystonia. However, the impacts of the genetic etiology of dystoni...
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 17/02/2025
Congratulations, Andreas! It's great news for European neuroscience to have you back and to have an institute dedicated to network stimulation! I hope to see you soon in Kobe and that you will tell me more about this.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 30/01/2025
Moreover, comparing our results with the literature on the efficacy of DBS in dystonia we observe that the reported efficacy seems to be proportional to the degree of burstiness associated with the genetic profile.
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 30/01/2025
Briefly, neural activities recorded during pallidal DBS implant from patients with different genetic profiles converge robustly in three clusters: one tonic firing group (AOPEP, PANK2, THAP1) one bursting group (GNAL, PLAG26, KMT2B, SGCE) and one highly irregular group (TOR1A, VPS16)
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 30/01/2025
Interested in #dystonia? Wondering how so many different genes can lead to this pathology? We might have found some answers analysing neural recordings from basal ganglia. Check our latest paper just out on Annals of Neurology: onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Spiking Patterns in the Globus Pallidus Highlight Convergent Neural Dynamics across Diverse Genetic Dystonia Syndromes
Objective Genetic dystonia is a complex movement disorder with diverse clinical manifestations resulting from pathogenic mutations in associated genes. A recent paradigm shift emphasizes the functio...
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Reposted by Alberto Mazzoni @Sant'Anna Pisa
Susanne Ahmari @ahmarilab.bsky.social · 23/01/2025
Article from @science.org re: today's freeze on #NIH study sections, Council, comms, hiring, travel www.science.org/content/arti...
science.org
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 22/01/2025
Conflict of interest disclosure: I was actually born in Florence
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 22/01/2025
A few days left for Tutorials and Workshops proposals submission for the 2025 meeting of the Organization for Computational Neuroscience. And this year the congress takes place in the most beautiful city of the world - you really can't miss it! www.cnsorg.org/cns-2025
cnsorg.org
CNS 2025
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 17/01/2025
For once we disagree my friend. Every aspect of Twin Peaks S3 is pure gold, including David Lynch role as Gordon Cole. "Who is the dreamer?"
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 09/01/2025
The amazing dataset of neural data from freely moving monkeys was collected by Luca Bonini's team at the University of Parma, and I performed the analysis with my incredible student Elena Hillary Rondoni from the Computational Neuroengineering Lab of Sant’Anna School of Advanced Studies in Pisa
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Alberto Mazzoni @Sant'Anna Pisa @albmazz.bsky.social · 09/01/2025
First post on @bsky.app to announce my first paper published @science.org! How much do we know about how the cortex encodes the same movement when it is performed in arbitrarily different contexts? Find out here: www.science.org/doi/10.1126/...
science.org
Neuroethology of natural actions in freely moving monkeys
The current understanding of primate natural action organization derives from laboratory experiments in restrained contexts (RCs) under the assumption that this knowledge generalizes to freely moving ...
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