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Aidan Lakshman

@ahl27.bsky.social
16 followers 10 following 4 posts

PhD Candidate in Bioinformatics at University of Pittsburgh I build methods for large scale comparative phylogenetics www.AHL27.com

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Aidan Lakshman @ahl27.bsky.social · 13/05/2025
EvoWeaver has been chosen as one of the "50 best recently published papers" in the "Computational and Theoretical Biology" collection at Nature Communications! Check out the full collection here: www.nature.com/collections/... Original paper: www.nature.com/articles/s41... #bioinformatics #rstats
nature.com
Computational and Theoretical Biology
As we navigate the era of big data in biological research, advanced computational techniques, such as mathematical models and machine learning algorithms, are ...
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Reposted by Aidan Lakshman
Prof Albé van der Merwe @albevdmerwe.bsky.social · 29/04/2025
Genome annotation is one of the things that we really need AI / machine learning to crack. New software makes it a little easier, but this one is a really interesting take on the problem. www.nature.com/articles/s41...
nature.com
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
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Reposted by Aidan Lakshman
Wright Laboratory @labofwright.bsky.social · 28/04/2025
Proud to announce a new publication from the lab: EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41...
nature.com
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
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Reposted by Aidan Lakshman
gEEK!a 🧬 🧪 @geeka.bsky.social · 24/04/2025
It's my absolute pleasure to say that we have a new paper from the lab out. This work uses evolutionary lineages to discover functional associations in proteins. We call it EvoWeaver. wrightlabscience.com/publications
wrightlabscience.com
Publications
scientific publications, bioinformatics, genomes, research, antibiotics, antibiotic resistance, genomics, evolution
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Reposted by Aidan Lakshman
Climate, Ecology, War & More: Dr. Glen Barry BigEarthData.ai @bigearthdata.ai · 24/04/2025
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals ->Nature | More info from EcoSearch
nature.com
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals
EvoWeaver is available as part of the SynExtend (v1.19.0) package74 for R75, which is distributed via the Bioconductor76 platform. A comprehensive description of input/output and examples of running each algorithm are contained in the supplementary R Markdown file available on...
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Reposted by Aidan Lakshman
Stephen Turner @stephenturner.us · 25/04/2025
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41... 🧬🖥️🧪 #Rstats bioconductor.org/packages/Syn...
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Reposted by Aidan Lakshman
Qian Cheng @qchengx1e3.bsky.social · 24/04/2025
EvoWeaver identifies genes working together using evolutionary information and infers protein functions using only genomic sequences. @ahl27.bsky.social @natcomms.nature.com www.nature.com/articles/s41...
nature.com
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
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Aidan Lakshman @ahl27.bsky.social · 18/12/2024
Wrapping up a project on #clustering #networks in #R (and #C) — I wrote a 4-part #blogpost on the stuff I learned. >1M nodes and >75M edges now runs with 500MB RAM in under 5min & billions of nodes are doable in under a day. Part 1 of the series is here: www.ahl27.com/posts/2024/1...
ahl27.com
Efficient File I/O, Part 1: Some (somewhat) surprising findings on C’s fseek
I’m working a lot with files for my latest research project, ExoLabel. I’ve (mostly) finished ensuring that the algorithm itself is accurate, so lately I’ve been turning my attention to optimizing its...
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