Sign in

Wright Laboratory

@labofwright.bsky.social
117 followers 28 following 21 posts

Bioinformatics Lab @DBMI Pitt Home of DECIPHER, SynExtend & SubTap #antibiotics #bioinformatics #evolution #evolution #R #Rstats See publications here: scholar.google.com/citations?user=2…

PostsRepliesMedia
Wright Laboratory @labofwright.bsky.social · 14/05/2025
Our EvoWeaver work is now included on the Computational and Theoretical Biology focus page of Nature Communications! The page highlights recent work that reports methodological advances in computational biology. www.nature.com/collections/...
nature.com
Computational and Theoretical Biology
As we navigate the era of big data in biological research, advanced computational techniques, such as mathematical models and machine learning algorithms, are ...
032
Wright Laboratory @labofwright.bsky.social · 28/04/2025
Proud to announce a new publication from the lab: EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals www.nature.com/articles/s41...
nature.com
EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
02212
Wright Laboratory @labofwright.bsky.social · 24/02/2025
🧪🧬🖥️ new paper: Tandem Repeats Provide Evidence for Convergent Evolution to Similar Protein Structures (doi.org/10.1093/gbe/...). You can also see the video explainer here: wrightlabscience.com/publications
doi.org
Tandem Repeats Provide Evidence for Convergent Evolution to Similar Protein Structures
Abstract. Homology is a key concept underpinning the comparison of sequences across organisms. Sequence-level homology is based on a statistical framework
2125
Wright Laboratory @labofwright.bsky.social · 01/10/2024
Nishant just came back from the EMSL at PNNL! wrightlabscience.com/news#oct2024
wrightlabscience.com
News
001
Wright Laboratory @labofwright.bsky.social · 23/09/2024
One of our recently published articles has gotten traction in the popular press: www.thehindu.com/sci-tech/sci...
thehindu.com
Vancomycin may not be able to treat MRSA infections for long
Researchers have found Staphylococcus aureus can adapt to vancomycin while overcoming its fitness cost, threatening the long-term use of vancomycin in the clinic.
001
Wright Laboratory @labofwright.bsky.social · 29/08/2024
New Paper Alert! VRSA can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability, from our Master's student (and his second paper published this month!). www.wrightlabscience.com/publications
wrightlabscience.com
Publications
scientific publications, bioinformatics, genomes, research, antibiotics, antibiotic resistance, genomics, evolution
001
Wright Laboratory @labofwright.bsky.social · 07/08/2024
One of the M.S. students got 2 papers accepted within days of each other! Here is one of them about #MachineLearning, #ElectronicHealthRecord Data, and #AntibioticResistance. #Bioinformatics has such a great place in our evolving healthcare landscape. 🧪 🧬🖥️
Infographic with topic headings about "Challenges Leveraging EHR for ML", Resistant Pathogen Prediction, Predicting Resistance to Multiple Antibiotics, Aiding Antimicrobial Stewardship." Read paper here: https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiae348/7712688
021
Wright Laboratory @labofwright.bsky.social · 15/07/2024
We are at #ISMB2024! Come say hi! (I'm probably the tallest person at the conference)
020
Wright Laboratory @labofwright.bsky.social · 01/05/2024
Updates to DECIPHER! It's now DECIPHERv3, with some cool updates! See wrightlabscience.com/news #bioinformatics #bioconductor #Genomics #biotechnology #R
Time to update to decipher v3.0
new search functions that are versatile, fast and in R
ultra-fast pairwise alignment
sequence databases now work wiht multiple flavors of SQL 
avaliable from bioconductor
001
Wright Laboratory @labofwright.bsky.social · 29/04/2024
One of the lab members was awarded funding to enhance and maintain #R #Biostrings. We're looking forward to seeing what he can do for the #bioinformatics community.
Post it with text: Aidan was awarded grant funding by the R Consortium's Infrastructure Steering Committee. This award will fund critical work to the Biostrings package for R, one of the foundational packages in the R bioinformatics community. This work will begin in June and take place over a year. By the end, he's expected to be the primary maintainer of Biostrings. Congrats Aidan!
001
Wright Laboratory @labofwright.bsky.social · 19/04/2024
Cool new paper released from the lab: Many purported pseudogenes in bacterial genomes are bona fide genes! wrightlabscience.com/publications
001
Wright Laboratory @labofwright.bsky.social · 01/04/2024
Hi All: We're looking for Post-Docs for our soggy lab for September. You don't have to already be a bioinformatician, as we are willing to train. We're especially interested in solving antibiotic resistance. Pls reach out w/ questions and share. We'd love to fill this position (we have 2). 🧪🖥️🧬
Wright Lab Recrutiting for Postdoctoral researchers. 3-4 year funded positions in informatics/genomics/EHR mining, antibiotic resistance, with access to clinical EHR data warehouse. Apply to eswright@pitt.edu, start in Sept, due April 29th.
062
Wright Laboratory @labofwright.bsky.social · 31/01/2024
GLBio24 is in Pittsburgh this year! Submissions are open! Submit to our "Big Biological Data" Special Session! 🧪
Graphic Reads GLBion 13-16May 2024
Call for Abstracts, Due March 4
Scalable Analysis for Big Biological Data
Hosted by wrightlabscience.com
001
Wright Laboratory @labofwright.bsky.social · 12/01/2024
Now that Spotify Wrapped has wrapped. Let's check out the Wright Lab Year In Review! 🧪
5 conferences attended, 10 manuscripts submitted, 2 papers published, 7 classes taken, 1045 years of computing on open science grid.
110
Wright Laboratory @labofwright.bsky.social · 09/11/2023
Turns out that popular AI suggests us not once, but 3 times for the same query on sequence alignments. www.wrightlabscience.com/index.html
wrightlabscience.com
Wright Lab
000
Wright Laboratory @labofwright.bsky.social · 03/10/2023
We're the Wright Lab at the University of Pittsburgh School of Medicine. We do evolution of antibiotic resistance in a 'soggy' (both dry and wet lab work) lab. Our under-construction website: www.wrightlabscience.com/p/index.html. We also have available T15 funding!
Person holding a wrapped petri dish with blue bacteria growing in a streaked pattern.
000
Wright Laboratory @labofwright.bsky.social · 20/09/2023
Our department is recruiting PhD students for the 2024 cohort! Come work with us in biomedical informatics. Our lab works on solutions to antibiotic resistance using computational methods. 🧪🧫🩺
Recruitment flyer for dbmi.pitt.edu Image is text describing phd in biomedical informatics
031
Wright Laboratory @labofwright.bsky.social · 11/09/2023
Hi! can we be added to the what's science feed/bioinformatics? @danirabaiotti.bsky.social (Also, thanks for curating!) 🧪. 🖥️ 🧬
120
Wright Laboratory @labofwright.bsky.social · 11/09/2023
Are you an undergrad looking for a grad program in the bioinformatics space? Are you interested in new, evolving problems in antibiotic resistance? We have funding. Come work with us! 🧪
Recruitment flyer for dbmi.pitt.edu
021