iiinova — where your digital self keeps evolving

Reposted by Anna Lehmann

Julian Liber @liberjulian.bsky.social · 26/08/2026

For all the fungi hunters out there, the Heitman Lab at Duke University is looking for Cryptococcus luteus found associated with crust fungi on fallen logs. Every sample helps! #mycology

A wanted poster for the fungus Granulobasidium vellereum and its parasite Cryptococcis luteus. Searchers should check the underside of fallen logs (especially elm) for white to cream crusts on the bottom side. The parasite appears as pale-yellow circular patches on the fungal surface. If found, searchers should record the location, host, take a photo, and send the whole branch/piece in a paper bag to the Heitman lab.

12311

Reposted by Anna Lehmann

garimasingh-gs.bsky.social @garimasingh-gs.bsky.social · 24/06/2026

🍄 New study on #fungal #isocyanide synthases (#ICSs)! With @grantnickles.bsky.social @kellerlab.bsky.social (Uni. Wisconsin-Madison) @currentbiology.bsky.social @unipd.bsky.social Thanks all for the great teamwork! doi.org/10.1016/j.cub.… #Lichens #SecondaryMetabolism #biosyntheticGenes #fungi

22013

Reposted by Anna Lehmann

Duke University School of Medicine @dukemedschool.bsky.social · 18/06/2026

Anna Lehmann, PhD candidate working in the Heitman Lab, found Aspergillus fumigatus can briefly duplicate chromosomes to survive antifungal treatment, then revert without a trace. medschool.duke.edu/news/phd-candida…

medschool.duke.edu

PhD candidate discovers a hidden way that a fungal pathogen may resist treatment

Some fungal pathogens survive antifungal drugs by mutating.

023

Reposted by Anna Lehmann

Michelle Momany @mcmomany.bsky.social · 13/06/2026

Big surprise just out from our lab. Transcriptome from A. fumigatus conidiophore made at 50C is upregulated for MAT1-1. Why is this sexual master regulator up in asexual development? Maybe priming future progeny for survival? www.biorxiv.org/content/10.6...

biorxiv.org

Temperature during Aspergillus fumigatus conidiophore development primes spore transcriptome for asexual, parasexual or sexual development

Aspergillus fumigatus is a thermotolerant saprobe found in soils and plant debris worldwide and an important pathogen of humans causing two million deaths annually. A. fumigatus makes abundant asexual...

0188

Reposted by Anna Lehmann

George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 21/11/2025

Excited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF. pubmed.ncbi.nlm.nih.gov/41256617/

1147

Anna Lehmann @aelehmann.bsky.social · 04/10/2025

Excited to share our new preprint in collaboration with @kellerlab.bsky.social! We identified unstable aneuploidy in Aspergillus fumigatus and explore how aneuploidy-mediated transcriptional and metabolic changes influence antifungal resistance. www.biorxiv.org/content/10.1...

biorxiv.org

Whole-chromosome duplications drive antimicrobial resistance in Aspergillus fumigatus

Aneuploidy causes genome plasticity and enables adaptive responses that confer drug resistance in eukaryotes ranging from fungal pathogens to human cancer cells. Aspergillus fumigatus is a soil-reside...

022

Reposted by Anna Lehmann

Vikas Yadav @vikasyadavsci.bsky.social · 20/08/2025

Extremely excited to present our latest preprint in which we mapped a thermoregulation network that governs virulence in a human fungal pathogen through genetic suppressors, TurboID proximity ligation assay, and functional regulation via domain-truncation alleles. www.biorxiv.org/content/10.1...

122

Reposted by Anna Lehmann

Neta Shlezinger @shlezingerlab.bsky.social · 14/08/2025

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in @natmicrobiol.nature.com uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

doi.org

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

59244