Adrien Tassou @adrtas.bsky.social · 08/08/2025Big news! My K99 application has been awarded 🥳🎉 I'm excited to work together with @zenbrainest.bsky.social and @MarkZylka to explore how distinct peripheral neuron types shape pain representation in the brain. 140
Adrien Tassou @adrtas.bsky.social · 09/02/2025🌟 Excited to share our new review published in RAPM ! 🌟 Happy to have worked with Cyril Rivat and Philippe Richebé on this piece of work in which we explore the mechanisms underlying chronic post-surgical pain. rapm.bmj.com/content/50/2...rapm.bmj.comMechanisms of chronic postsurgical painChronic pain after surgery, also known as chronic postsurgical pain (CPSP), is recognized as a significant public health issue with serious medical and economic consequences. Current research on CPSP ... 130
Reposted by Adrien TassouRobert Gereau @robgereau.bsky.social · 30/01/2025A big day for pain care, and for pain science. www.fda.gov/news-events/...fda.govFDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute PainThe FDA approved Journavx (suzetrigine) 50 mg oral tablets, a first-in-class non-opioid analgesic to treat moderate to severe acute pain in adults. 03416
Reposted by Adrien TassouMatan Geron @mgeron.bsky.social · 07/12/2024I am glad to share our recent work, now published in Cell! A @zenbrainest.bsky.social and Scherrer lab collaboration developing and validating a new peripherally restricted DREADD system! Great team work with Hye Jin Kang, Brian Krumm, @adrtas.bsky.social, and others www.cell.com/cell/abstrac...cell.comStructure-guided design of a peripherally restricted chemogenetic systemKang et al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system. 0146
