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Anne C. Hart

@ach-ceneuro.bsky.social
946 followers 803 following 132 posts

Neuroscientist, geneticist, educator, mentor, loves C. elegans, puns, birds, sci-fi/fantasy and kinda nerdy. You get my personal opinions here! 🌈

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Reposted by Anne C. Hart
Nicolas Lux Fawzi @nicolasluxfawzi.bsky.social · 11/10/2026
Brown University is hiring an Assistant Professor in Structural Biology apply.interfolio.com/193082
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Anne C. Hart @ach-ceneuro.bsky.social · 30/09/2026
Position available to work on Alternating Hemiplegia of Childhood; develop assays & test compounds using Hart lab #Celegans disease models. Ideal for scientist with Bachelors or Masters degree seeking mentorship, but previous at-the-bench experience is required. See REQ211438 on Brown Univ website.
C. elegans, various life stages
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Anne C. Hart @ach-ceneuro.bsky.social · 01/09/2026
This is normal. Sad, but normal
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Anne C. Hart @ach-ceneuro.bsky.social · 21/08/2026
Agree. For my flipped class, I’ll assign a paper & if there are techniques I don’t want to go into depth on, then I’ll just include links to short technique descriptions—so students watch these online in advance. Saves time in class…
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Anne C. Hart @ach-ceneuro.bsky.social · 07/08/2026
So much summer research at Brown - this year, they had to split the Summer Research Symposium across 2 days with multiple sessions on each day. Five amazing students presented posters from the Hart Lab!
Five students with posters from the Brown Summer Research Symposium
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Anne C. Hart @ach-ceneuro.bsky.social · 22/07/2026
Scientists and family foundations working together on cutting-edge approaches to cure rare childhood diseases. www.nytimes.com/2026/07/21/h...
nytimes.com
‘Too Rare to Care’? A New Center for Rare Diseases Hopes to Change That (Gift Article)
A new nonprofit wants to streamline gene therapy for diseases often avoided by pharmaceutical companies — making treatment more like a routine procedure than a bespoke drug.
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Anne C. Hart @ach-ceneuro.bsky.social · 21/07/2026
Duralux glass plates and glasses made in France are still excellent quality. Thanks for this summary article that confirms the shocking quality drop in dishes, cookware, etc
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Anne C. Hart @ach-ceneuro.bsky.social · 14/07/2026
Today is a great day to register for your Fall election mail-in ballots, especially if you can’t vote early or in-person…
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Anne C. Hart @ach-ceneuro.bsky.social · 11/07/2026
Why is Trump suddenly okay with helping Ukraine fight Russia?
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Anne C. Hart @ach-ceneuro.bsky.social · 26/06/2026
Laughing & crying simultaneously. This is hilarious… 👍👍
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Anne C. Hart @ach-ceneuro.bsky.social · 23/06/2026
@bskyplays.bsky.social zork
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Reposted by Anne C. Hart
Victor Ambros @vambros.bsky.social · 20/06/2026
A column by Jeff Coller: “The Science That Turned Lizard Venom Into GLP-1s Is Under Attack” www.nytimes.com/2026/06/20/o...
nytimes.com
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
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Anne C. Hart @ach-ceneuro.bsky.social · 19/06/2026
Forgot to add #Postdoc #PostdocJobs !!
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Anne C. Hart @ach-ceneuro.bsky.social · 17/06/2026
Postdoctoral position available, focused on Alternating Hemiplegia of Childhood! Join the awesome Brown Univ. neuroscience community. Background in genetics (like C. elegans) and/or neuroscience is welcome, but not required. Contact Anne Hart for details and apply via apply.interfolio.com/188268
Cover image from Dis Model Mech (2026) Volume 19, Issue 5 showing C. elegans population on a Petri dish, associated with article: https://doi.org/10.1242/dmm.052809
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Anne C. Hart @ach-ceneuro.bsky.social · 17/06/2026
The cup is oriented incorrectly. It’s a hound dog looking away from you. So, good news: “In the art of tea leaf reading (tasseography), a dog generally symbolizes loyalty, friendship, and trusted companions”
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Anne C. Hart @ach-ceneuro.bsky.social · 12/06/2026
This template was incredibly helpful for knowing which sections of the OMB proposal we should criticize in our comments, and why. Thanks!
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Anne C. Hart @ach-ceneuro.bsky.social · 11/06/2026
Ouch
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Anne C. Hart @ach-ceneuro.bsky.social · 05/06/2026
New! C. elegans models for Alternating Hemiplegia of Childhood; project led by Diana Wall, PhD at Brown University. All models show dominant defects, but each disease variant has unique defects…paralleling AHC patient allele differences #AHC #DMM #Celegans
journals.biologists.com
Caenorhabditis elegans models of alternating hemiplegia of childhood have dominant neuromuscular junction defects
Summary: We report the first C. elegans models of alternating hemiplegia of childhood. D801N, E815K, L839P and G947R AHC model animals have recessive development defects and dominant neuromuscular def...
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Anne C. Hart @ach-ceneuro.bsky.social · 02/06/2026
Guess I’ll just go back to thumbing through my copy of Tufte and look again at his examples of “what not to do…” www.edwardtufte.com/book/the-vis...
edwardtufte.com
The Visual Display of Quantitative Information | Edward Tufte
The classic book on statistical graphics, charts, tables. Theory and practice in the design of data graphics, 250 illustrations of the best (and a few of the worst) statistical graphics, with detailed...
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Anne C. Hart @ach-ceneuro.bsky.social · 02/06/2026
Oh! Now I’m excited! I would love an invitation to this channel…
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Anne C. Hart @ach-ceneuro.bsky.social · 30/05/2026
TBH, Colbert could run a late night TV show on PBS and the audience would follow him. Win-win for PBS, Colbert, and democracy…
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Reposted by Anne C. Hart
Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 25/05/2026
Dearest shoalmates: Please consider posting a comment to the NIH regarding the Strategic Plan that includes reducing funding for animal research. Responses from the research community are currently greatly underrepresented compared w/ advocacy groups opposing animal experimentation. 🔗 below ⬇️ 1/2
Image of racks of zebrafish tanks. Credit to NC3Rs. https://www.nc3rs.org.uk/events/guide-refinement-fish-species
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Anne C. Hart @ach-ceneuro.bsky.social · 23/05/2026
Truthiness…
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Anne C. Hart @ach-ceneuro.bsky.social · 01/02/2026
Alt plan for the JF Kennedy Center for the Performing Arts to avoid a 2 year shut down: 1) let @brucespringsteen.net pick a new Board of Directors and 2) give us 20min, a ladder & chisels to fix the front of the building.
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Anne C. Hart @ach-ceneuro.bsky.social · 01/02/2026
Thanks for posting this. I’ve let my neighbors know & we all shoveled together to prepare
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Anne C. Hart @ach-ceneuro.bsky.social · 31/01/2026
You know who isn’t in the Epstein file: Kamala Harris and Tim Walz
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Anne C. Hart @ach-ceneuro.bsky.social · 31/01/2026
Maybe I’ll go watch the Terminator movies again…
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Anne C. Hart @ach-ceneuro.bsky.social · 31/01/2026
www.forbes.com/sites/amirhu...
forbes.com
An Agent Revolt: Moltbook Is Not A Good Idea
OpenClaw is a breakthrough AI assistant. Moltbook, its new social network for agents, is a security catastrophe waiting to happen. Here's why you should avoid it.
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Anne C. Hart @ach-ceneuro.bsky.social · 26/01/2026
I feel seen.
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Anne C. Hart @ach-ceneuro.bsky.social · 25/01/2026
Waiting to see if professional athletes in the USA have the courage to start protesting during the national anthem…
media.tenor.com
a group of football players are kneeling on the field and one of them has the number 7 on his jersey .
Alt: Colin Kaepernick in a group of football players kneeling on the field during national anthem.
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Reposted by Anne C. Hart
Alt CDC (they/them) @altcdc.altgov.info · 10/01/2026
🧵1/4 🚨 WEEKEND APPEAL 🚨 We need hundreds more public comments on a harmful proposed rule. 🗓️ Due Jan 29 OPM (aka Vought 🤮💩) is proposing changes that make it easier to fire probationary employees and much harder to appeal. OPM = Office of Personnel Management 🔗 www.regulations.gov/document/OPM...
regulations.gov
Regulations.gov
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Anne C. Hart @ach-ceneuro.bsky.social · 18/12/2025
Sometimes, I let the journal know I will be able to handle a review next month…
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Anne C. Hart @ach-ceneuro.bsky.social · 26/11/2025
Adding -ai also works. Being able to avoid the AI is a blessing
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Anne C. Hart @ach-ceneuro.bsky.social · 25/11/2025
In my experience, when grad school applicants are considered, essays & letters of rec are more important than anything else in the application. They outweigh GPA, scores, etc. We are very grateful that y’all put so much effort into writing these thoughtful letters ❤️
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Anne C. Hart @ach-ceneuro.bsky.social · 21/11/2025
My gold standard: “two purified proteins bind in a tube” by any detection method, or FRET in vivo. Two hybrid interaction in yeast is almost adequate. IP is not evidence of direct interaction, just coexistence in a complex (unless purified proteins in a tube). IHC does not convince…
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Anne C. Hart @ach-ceneuro.bsky.social · 12/11/2025
50 years mortgages will massively increase profit for banks and give real estate developers so many opportunities to scam people and the IRS. No wonder Trump likes the idea…
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Anne C. Hart @ach-ceneuro.bsky.social · 29/10/2025
Oh! SNAP!
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Anne C. Hart @ach-ceneuro.bsky.social · 25/10/2025
Wow. The timeline on the official White House page wildly veers into a political smear campaign when you reach 1998…
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Anne C. Hart @ach-ceneuro.bsky.social · 25/10/2025
media.tenor.com
a baby is sitting in a crowd with a woman holding him and screaming yes .
ALT: a baby is sitting in a crowd with a woman holding him and screaming yes .
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Anne C. Hart @ach-ceneuro.bsky.social · 24/10/2025
Acadia is amazing in summer. Fall must be astonishing…
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Anne C. Hart @ach-ceneuro.bsky.social · 21/10/2025
Extra credit if he is currently an ICE employee…
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Reposted by Anne C. Hart
Bess Frost @bessfrost.bsky.social · 10/10/2025
We are excited to announce a new open search for a tenure track Assistant Professor position within the Brown University Center for Alzheimer's Disease Research! Apply here: apply.interfolio.com/175427
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Reposted by Anne C. Hart
Antebi Lab @antebilab.bsky.social · 08/10/2025
🚨New @biorxivpreprint: We model the splicing factor disease Verheij syndrome using C. elegans. Disruption of methionine and phospholipid metabolism drives growth defects; vitamin #B12 restores metabolic balance and rescues development! #metabolism #Celegans #RNAsplicing doi.org/10.1101/2025...
doi.org
Vitamin B12 alleviates Verheij syndrome-like defects via phospholipid remodeling in a C. elegans PUF60 spliceosomopathy model
Verheij syndrome (VRJS) is a rare genetic disorder caused by mutations in the poly(U)-binding splicing factor 60 (PUF60), a core component of the spliceosomal complex. VRJS triggers multiple congenita...
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Anne C. Hart @ach-ceneuro.bsky.social · 08/10/2025
Beautiful work!
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Anne C. Hart @ach-ceneuro.bsky.social · 07/10/2025
Why not require more “flipped” classes — pre-recorded lectures & mandatory in-class work, such as small group problem solving, peer-to-peer presentations, daily quizzes, discussing primary literature? Clearly, I’m not a fan of letting students enroll in two classes that meet at the same time
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Reposted by Anne C. Hart
Victor Ambros @vambros.bsky.social · 04/10/2025
Are you an alum from one of the 9 schools Trump just attacked? Sign this alumni petition now to support your school, defend democracy, and build a grassroots movement for campus freedom across America. alumni.controlshift.app/petitions/tr...
alumni.controlshift.app
STAND WITH YOUR SCHOOL: Trump attacks 9 universities. Sign the alumni petition now.
Are you an alum from one of the 9 schools Trump just attacked? Sign this alumni petition now to support your school, defend democracy, and build a grassroots movement for campus freedom across America...
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Anne C. Hart @ach-ceneuro.bsky.social · 30/09/2025
Panicked cat learning password must contain number letter symbol, gang sign, haiku, hieroglyphic, and blood of a virgin
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Anne C. Hart @ach-ceneuro.bsky.social · 30/09/2025
Hesgeth forced our senior military officials to travel back to Quantico for his nonsense “speech”. Our generals know that this was a total waste of their time — but they are too professional, disciplined and tactical to announce their opinions in public…for now.
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Anne C. Hart @ach-ceneuro.bsky.social · 25/09/2025
All of these are good ideas. I can personally confirm how useful 4% of these tips are…🤣
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