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Alex Bradu

@abradu.bsky.social
14 followers 58 following 3 posts

uchicago ‘23 | nyc | satija lab RA | she/her 🧬 👩🏻‍🔬🔬

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Alex Bradu @abradu.bsky.social · 17/02/2026
Huge thanks to everyone in the Satija lab (especially my co-first author @jblairsci.bsky.social) and everyone else who’s taken the time over the past year to chat with us about the project. Check out the full preprint here: www.biorxiv.org/content/10.6... [3/3]
biorxiv.org
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Alex Bradu @abradu.bsky.social · 17/02/2026
We hope this method represents a step towards democratizing single-cell screens, and helps to make it possible to run genome-wide scale experiments routinely. To that end, we've put together a webpage with resources for labs interested in trying VIPerturb-seq here: satijalab.org/viperturb-seq/ [2/3]
satijalab.org
VIPerturb-seq
VIPerturb-seq # A platform for routine genome-wide single-cell CRISPR screens # We’re excited to introduce VIPerturb-seq, a technology that enables cost-effective, genome-wide pooled CRISPR screens wi...
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Alex Bradu @abradu.bsky.social · 17/02/2026
Roses are red 🌹, pipettes are gray 🔬, Our preprint is live on bioRxiv today! 🎊 I’m thrilled to share that our work introducing VIPerturb-seq, a new platform for single-cell pooled screens built with @10xgenomics.bsky.social Flex, came out on @biorxivpreprint.bsky.social this Valentine's Day [1/3]
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Reposted by Alex Bradu
Nature @nature.com · 25/08/2025
Nature research paper: Thymic epithelial cells amplify epigenetic noise to promote immune tolerance go.nature.com/41TUQLE
go.nature.com
Thymic epithelial cells amplify epigenetic noise to promote immune tolerance - Nature
The activity of the tumour-suppressor protein p53 is repressed in the thymus to augment fluctuations in background chromatin accessibility as a means of mediating ectopic gene expression and immune tolerance.
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