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Alex Bradu

@abradu.bsky.social

uchicago ‘23 | nyc | satija lab RA | she/her 🧬 👩🏻‍🔬🔬

Alex Bradu @abradu.bsky.social · 17/02/2026

Roses are red 🌹, pipettes are gray 🔬, Our preprint is live on bioRxiv today! 🎊 I’m thrilled to share that our work introducing VIPerturb-seq, a new platform for single-cell pooled screens built with @10xgenomics.bsky.social Flex, came out on @biorxivpreprint.bsky.social this Valentine's Day [1/3]

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Reposted by Alex Bradu

Nature @nature.com · 25/08/2025

Nature research paper: Thymic epithelial cells amplify epigenetic noise to promote immune tolerance go.nature.com/41TUQLE

go.nature.com

Thymic epithelial cells amplify epigenetic noise to promote immune tolerance - Nature

The activity of the tumour-suppressor protein p53 is repressed in the thymus to augment fluctuations in background chromatin accessibility as a means of mediating ectopic gene expression and immune tolerance.

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