For decades, the field has known that when ER cholesterol increases, SCAP binds INSIG and SREBP2 is silenced. In our new work, we propose that cholesterol esterification provides the missing physical mechanism.
Abdou Rachid Thiam
@abdourachidthiam.bsky.social
173 followers 150 following 46 posts
@CNRS Research Director @ENS_ULM. Interested in Droplets, Metabolism, Organelles, Lipids, BioPhysics, Microfluidics & Co, 🇸🇳
