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Alec Bahcheli

@abahcheli.bsky.social
13 followers 17 following 0 posts

Full time scientist, part time pilot

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Reposted by Alec Bahcheli
Jüri Reimand @reimand.bsky.social · 15/02/2026
Somatic mutational signatures describe where mutations come from 🧬. But do they shape how proteins function? In our new preprint, we show that mutational processes can systematically rewire cellular signaling networks by altering short linear motifs (SLiMs). Preprint: www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Alec Bahcheli
Jüri Reimand @reimand.bsky.social · 08/07/2025
Another great collaboration with Carolina Nor & Michael Taylor: Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process. @abahcheli.bsky.social led our omics integration via pathway analyses. @cp-devcell.bsky.social www.cell.com/developmenta...
cell.com
Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process
Radiation, the most effective treatment for medulloblastoma, induces an innate immune response and opens the blood-brain barrier, allowing for the intravasation of tumor cells into the blood circulati...
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Reposted by Alec Bahcheli
Jüri Reimand @reimand.bsky.social · 09/05/2025
very happy to have contributed to this collaboration with the Taylor lab - with integrative pathway analyses & rich network visualizations led by our PhD student @abahcheli.bsky.social
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