Sign in

Athanasios Alexandris, MBChB

@a-alexandris.bsky.social
114 followers 221 following 8 posts

#Neuroscientist, #Physician - #Axons, #Neurodegeneration, #TBI. 🧠 Research Associate. @JohnsHopkins @JHUPath. (He/him)

PostsRepliesMedia
Athanasios Alexandris, MBChB @a-alexandris.bsky.social · 05/02/2026
Thanks to Speaking Out for the Blind for the opportunity to talk about our work on collateral sprouting and recovery after injury in the visual system. speaking-out-for-the-blind.pinecast.co/episode/c88d...
speaking-out-for-the-blind.pinecast.co
Speaking Out for the Blind Episode 380- Mammals Restoring Vision
Popular Mechanics says that mammals may not have ocular regeneration superpowers. But a new study shows that nature might have a couple of tricks up its sleeve. Joining me to talk about the recent stu...
030
Athanasios Alexandris, MBChB @a-alexandris.bsky.social · 16/12/2025
Thrilled that our new paper is now out !
031
Reposted by Athanasios Alexandris, MBChB
BWJones @bwjones.bsky.social · 09/12/2025
It’s @a-alexandris.bsky.social talking at the Retinal Ganglion Cell Meeting about his work in axonal degeneration.
072
Athanasios Alexandris, MBChB @a-alexandris.bsky.social · 03/07/2025
In our new study (doi.org/10.1093/jnen...), we map high-resolution changes in the visual system in the EAE model of MS. Early deficits in axonal transport and function occur before overt axon or RGC loss, highlighting a window for axon-targeted neuroprotection in demyelinating disease. 1/5
doi.org
Temporal progression of axonal degeneration in the visual system in experimental autoimmune encephalomyelitis: Insights from high-resolution neuropathology
Abstract. Multiple sclerosis (MS) is characterized by inflammation, demyelination, and axonal degeneration in the CNS, leading to progressive neurological
120
Reposted by Athanasios Alexandris, MBChB
DeshmukhLab @deshmukhlab.bsky.social · 18/04/2025
doi.org/10.1038/s443...
doi.org
The NLRP1 inflammasome is an essential and selective mediator of axon pruning in neurons | EMBO reports
imageimageAxon pruning, the selective degeneration of axons, requires many apoptotic proteins, though it is distinct from apoptosis. This study identifies two inflammasome proteins, Caspase-1 and NLRP...
011
Athanasios Alexandris, MBChB @a-alexandris.bsky.social · 31/12/2024
Our new paper is out! Even with helmet protection, high-energy blunt trauma can lead to fatal respiratory failure. Our study maps specific brainstem injury patterns, revealing critical implications for #TBI & protection. Patterns of #vascularinjury ≠ #axonalinjury www.liebertpub.com/doi/10.1089/...
liebertpub.com
Diffuse Axonal and Vascular Pathology in the Gyrencephalic Brain after High-Energy Blunt Injury: Clinicopathological Correlations Involving the Brainstem | Journal of Neurotrauma
Traumatic brain injury (TBI) after high-energy, behind helmet blunt trauma (BHBT) is an important but poorly understood clinical entity often associated with apnea and death in humans. In this study, ...
082