In our new paper, we used data from 500+ infections to show that disease outcomes aren’t random but cluster into distinct archetypes reflecting tradeoffs between immunity and tolerance. A simple host-pathogen model reproduces these shapes, offering a geometric lens on immune strategies.
science.org
From Plato to Pareto: Defining the shape of infection’s disease space
All malaria outcomes fall within a tetrahedron in microbe-by-immunity-by-damage space.
