Duke surgical oncologist Jennifer Plichta, MD, MS, is pushing the evolution of personalized care — combining data, research, and a deeply patient-centered approach to help patients navigate an increas...

A discovery that began in a Duke laboratory is now being tested in Duke patients, offering a potential new approach to diagnosing cardiac sarcoidosis, which can be life-threatening and difficult to di...

New research from Duke University School of Medicine points to a surprising possibility: a naturally occurring human gut bacterium produces a sugar molecule that helps obese mice increase energy expen...

A team led by Duke neonatologist Noelle Younge, MD, MHS, has found evidence that the intestinal microbiome plays a direct role in slow weight gain and poor growth in preterm infants.

When you feel toothpaste's minty tingle, it's caused by the opening of a molecular "door" found in sensory nerve cells in your mouth. In 2022, Duke biochemists captured images of this door, a protein ...

E-cigarettes help many smokers quit. Duke researchers say there’s a catch.

Small cell lung cancer is aggressive and often spreads before it’s detected. About 70% of patients have metastatic cancer at diagnosis, and the five-year survival rate remains roughly 7%. Now Duke Uni...

Researchers are studying rare moments when people with advanced dementia suddenly regain clarity, memory or function

Wearing newly issued white coats and stethoscopes, 120 students joined Duke University School of Medicine's incoming class during a ceremony that marked their formal entry into the medical profession....

What if pain relief and addiction didn't have to go hand in hand? Duke researchers report a discovery that could help scientists design safer opioids. Their Nature study found that a small group of br...

The tool, called Raygun in a nod to science fiction, can create shorter, longer, and highly modified versions of proteins while preserving their structure and function. The findings, published in Natu...

Missed mortgage payments? Drop in credit score? Researchers find new markers for suicide risk.

The teen years may be a critical window when the gut microbiome and its influence on weight is still taking shape and more open to change.

Debra Silver, PhD, is pursuing one of neuroscience’s biggest questions: What makes a human brain human? She researches it with the same mix of precision and adventure she brings to her passion for scu...

A new study suggests what’s flushed down the drain can offer a real-time snapshot of what communities are eating. Researchers at Duke University School of Medicine and the University of North Carolina...

Study finds rapid weight loss before body contouring surgery may raise complication risk.

Duke researcher Leah Acker, MD, PhD, is studying how repeated stress and inflammation in the body can quietly build up over time, creating an “inflammatory hangover” that may speed up brain aging and ...

New weight-loss drugs that combine natural gut hormones are helping people lose significant weight and better control blood sugar, but scientists are still working to understand exactly how they work....

Some fungal pathogens survive antifungal drugs by mutating.

Beth A. Sullivan, PhD, has been appointed vice dean for basic and preclinical science at Duke University School of Medicine, effective July 1, 2026.

Team from Duke University School of Medicine and Duke NUS identify an enzyme that helps explain why muscles weaken in some cancer patients.

Instead of treating numbers in the moment, new cholesterol guidelines emphasize lifetime exposure by urging patients to reach lower LDL levels sooner and keep them there. Cardiologists are now mapping...

Aging is increasingly seen as a lifelong process that we can influence and alter to a remarkable degree. Researchers are learning more every day about the complex metabolic, cellular, and molecular pr...

Duke researchers Sundarshan Rajagopal, MD, PhD, and MD-PhD student Preston Anderson have worked together to realize how G protein-coupled receptors signal through liquid-like protein clusters that cou...

Scientists have long known that aging leaves its mark throughout the body — from fraying DNA to a slowing immune system. Now, a growing wave of research suggests an unexpected starting point for some ...

Osteoarthritis is a common condition where the cartilage that cushions joints breaks down over time, leading to pain and stiffness, especially as people age. Duke researchers are working on ways to go...

Carrie Brown, MD'04, HS'04-'08, MPH, credits her first clinical rotation as a Duke University medical student at John Umstead Hospital, a former psychiatric inpatient facility in Butner, North Carolin...

Study pinpoints a single brain connection in songbirds that helps turn practice into skill, offering one of the clearest explanations yet of how the brain learns complex behaviors like speech and musi...

Broken or disrupted circuits in the brain contribute to many neurological disorders. A new custom-built biological “wire” developed at Duke University School of Medicine points the way toward a new tr...

Study reveals ascites is more than a patient symptom, but an active player in helping ovarian cancer spread and grow.

With philanthropic support, Duke University aims to turn innovative ideas into real-world solutions for the growing health impacts of climate change.

A study from cancer biologists at Duke University School of Medicine suggests a new way to predict which patients are most likely to benefit from a promising class of experimental cancer drugs called ...

Team from Duke University School of Medicine and Duke NUS identify an enzyme that helps explain why muscles weaken in some cancer patients.