iiinova — where your digital self keeps evolving

Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 06/07/2026

Shoutout to the speakers for their fantastic talks today: Petros kicked the day off, followed by Melanie Mendel, @kamounlab.bsky.social, Francine Govers and Martijn Rep

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 06/07/2026

Today we're enjoying a wonderful symposium hosted by Petros Skiadas & @mfseidl.bsky.social, as a prelude for Petros's PhD defence. Lots to learn about oomycetes and plant pathogenesis, immunity and effector biology! @ubc-uu.bsky.social @utrechtuniversity.bsky.social

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 13/05/2026

Proud of @ehauptfeld.bsky.social for receiving the Young Investigator Award by @biosb.bsky.social, in recognition to her PhD achievements in research and education! Very well deserved, and congratulations! @ubc-uu.bsky.social @utrechtuniversity.bsky.social

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 05/05/2026

It allows us to tap into the solutions plants evolved to deal with the (harsh) environment they are exposed to, as we demonstrate by revealing the genetic basis of hypocotyl elongation in 20°C and 28°C.

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 05/05/2026

The 'EcoCore panel' was designed by grouping natural accessions based on their native collection environment, and is enriched for rare and potentially relevant alleles from specific environments that are underrepresented in broader collections

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 09/12/2025

In this approach, the defective virus competes with the normal virus for shared proteins, which suppresses viral replication. Using mathematical modeling, they found that while this treatment is promising, a protective immune response drastically reduces its effectiveness. #mathbio #immunobio

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 03/09/2025

Using this methodology, they recovered both known and many novel QTLs for color and height, opening up new breeding targets. This study represents a blueprint for high-throughput genetics studies, with the entire methodology as well as all the raw data fully and conveniently available.

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 03/09/2025

They used an innovative GWAS approach involving the construction of many traits as ratios of the imaging data and quantifying these traits using various summary statistics. They then optimized the GWAS for computational efficiency to facilitate mapping this large number of traits.

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 12/06/2025

Paulien Hogeweg was Rob's supervisor during his MSc and PhD. She kicks off the meeting by reminiscing about Rob's beginnings: "First students are special, especially those who become a lifelong colleague, successor, and now, fellow emeritus"

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 12/06/2025

Today we celebrate over 40 years of research of Rob de Boer, chair Professor of Theoretical Biology. Rob complemented his tremendous scientific career with a deep impact in multiple roles, as a dedicated teacher, an inspiring mentor, and a kind and generous colleague. Thank you, Rob!

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 06/03/2025

📣 New article on the chimeric evolutionary origins of eukaryotic central carbon metabolism, by @santanamolina.bsky.social @tweethinking.bsky.social Berend Snel and @anja1.bsky.social Now out in @natureecoevo.bsky.social www.nature.com/articles/s41... #mevosky #microsky #archaeasky

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 25/11/2024

Theoretical Biology and Bioinformatics at the protest against the budget cuts on education. This choice will cost - everyone - money in the long run. #WOinActie #wanbeleid

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 25/11/2024

All the trains towards the protest against the budget cuts were full, so we’re taking a detour in this relatively empty train. This plan will not save money. This plan will cost money. It will cost - EVERYONE - money. #WOinActie @woinactie.bsky.social

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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 02/01/2024

With a complex developmental program, eQTL mapping can be challenging, as changes in gene expression complicate interpretation. Check out this new paper in G3 by Bram van Eijnatten, Basten Snoek and collaborators from Wageningen University & Research, and see how we can improve detection of eQTLs!

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