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Reposted by Sota Kuno

Cerebellum Science Center @cerebellumcenter.bsky.social · 11/07/2025

Excited to share our latest Nature publication, headed by the Pacold lab. Our experimental compound shows great promise as a novel, mechanistic treatment for a pediatric disorder that can prove fatal. It also highlights the therapeutic relevance of the cerebellum. #neuroskyence tinyurl.com/yh9736m9

nature.com

Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy - Nature

Decreased brain coenzyme Q10 levels cause encephalopathy and are associated with neurodegeneration; supplementation with 4-HMA or 4-HB restores coenzyme Q10 synthesis in mice and humans with HPDL vari...

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