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Philipp Zimmer

@50823zimmer.bsky.social
98 followers 130 following 8 posts

Professor at TU Dortmund University | We do research on exercise immunology and tryptophan metabolism in health and disease scholar.google.de/citations?user=j8…

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Philipp Zimmer @50823zimmer.bsky.social · 21/09/2025
In this fantastic collaborative project with colleagues from Norway, @tu-dortmund.bsky.social @au.dk @uni-saarland.de, our outstanding PhD student @mkupjetz.bsky.social has shed light on distinct kynurenine pathway patterns in persons with #multiplesclerosis. www.neurology.org/doi/10.1212/...
neurology.org
Persons With Multiple Sclerosis Reveal Distinct Kynurenine Pathway Metabolite Patterns | Neurology Neuroimmunology & Neuroinflammation
Background and ObjectivesKynurenine pathway (KP) metabolites modulate inflammatory activity and neuronal viability. The consequences of KP imbalance partly resemble the molecular mechanisms of multipl...
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TU Dortmund @tu-dortmund.de · 22/05/2025
Welchen Einfluss hat Sport auf unsere Gesundheit? Lassen sich Immunzellen durch gezieltes Training beeinflussen? Kann man Sport sogar MS-Patienten Linderung verschaffen? Daran forschen Prof. Philipp Zimmer vom Institut für Sport und Sportwissenschaft & sein Team. www.youtube.com/watch?v=h58Y...
youtube.com
Research Snapshots: Sportimmunologie
YouTube video by TU Dortmund
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Niklas Joisten @niklasjoisten.bsky.social · 04/04/2025
Check out our new paper now out in Acta Physiologica on the tryptophan metabolite 3-HAA in the aging and exercise context 👇 @50823zimmer.bsky.social @davidwalzik.bsky.social onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Exercise training restores longevity‐associated tryptophan metabolite 3‐hydroxyanthranilic acid levels in middle‐aged adults
Aim Recent pre-clinical evidence suggests that the tryptophan metabolite 3-hydroxyanthranilic acid (3-HAA) and the related enzyme activity along the kynurenine metabolic pathway (KP) are associated ...
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Seth Thomas Scanlon @immunoeditor.bsky.social · 21/02/2025
This week in #Science #Immunology: researchers @ @helsinki.fi characterize #immune landscape of deep cervical #LymphNodes in newly diagnosed untreated patients w #MultipleSclerosis! Authors uncover several lines of evidence strengthening possible link btw #MS & Epstein–Barr virus ( #EBV ) infection!
science.org
Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
Deep cervical lymph nodes of patients with MS have an altered B cell compartment that, in part, transcriptionally resembles an EBV infection.
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David Walzik @davidwalzik.bsky.social · 05/02/2025
Happy to share our new preprint, where we investigate the impact of acute exercise on the proteome of immune cell! Comparing high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE), we found numerous proteins that were differentially expressed in PBMCs. (1/12)
medrxiv.org
Acute exercise rewires the proteomic landscape of human immune cells
Exercise-driven alterations of the immune system are a key mechanism in the prevention and treatment of various diseases. Here, we performed mass spectrometry-based proteomics analysis on peripheral b...
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medRxivpreprint @medrxivpreprint.bsky.social · 04/02/2025
Acute exercise rewires the proteomic landscape of human immune cells www.medrxiv.org/content/10.1101/202…
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Philipp Zimmer @50823zimmer.bsky.social · 28/01/2025
While first countries blacklisted MDPI for their unserious and harmful publishing culture, German universities signed contracts with this china hosted predator publisher…what a waste of tax payer money! www.mdpi.com/about/announ...
mdpi.com
Over 100 German Universities Partner with MDPI in New National Agreement
More than 100 German universities and research institutions have entered into a national agreement with MDPI. The publication agreement negotiated...
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Maarten van Smeden @maartenvsmeden.bsky.social · 27/01/2025
And there is this.... bsky.app/profile/carl...
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Maarten van Smeden @maartenvsmeden.bsky.social · 27/01/2025
Scientific publishing cannot be free but an annual $2.5 billion seems excessive to me
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Philipp Zimmer @50823zimmer.bsky.social · 30/12/2024
Finding the right journal is crucial and may influence careers! Of note first countries have blacklisted some publishers. A must read for all PIs, Post Docs and PhD Students: direct.mit.edu/qss/article/...
direct.mit.edu
The strain on scientific publishing
Abstract. Scientists are increasingly overwhelmed by the volume of articles being published. The total number of articles indexed in Scopus and Web of Science has grown exponentially in recent years; ...
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Philipp Zimmer @50823zimmer.bsky.social · 14/12/2024
Unbelievable to see our second @BrainBehavImm paper out in 2024🍾 @S_Proschinger @SergenBelen @maritschlagheck @TU_Dortmund and @SpohoKoeln 💪 Here we show that multimodal exercise training provokes Natalizumab-like effects in MS: sciencedirect.com/science/articl…
sciencedirect.com
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David Walzik @davidwalzik.bsky.social · 04/12/2024
How does exercise exert preventive and therapeutic effects in different diseases? What is the molecular basis of these effects and how are exercise signals mediated on a cellular level? A 🧵on our lates review in Signal Transduction and Targeted Therapy: (1/13)
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David Walzik @davidwalzik.bsky.social · 04/12/2024
Thanks a lot to @50823zimmer.bsky.social and @niklasjoisten.bsky.social for the great supervision and input along the way and to Tiffany for the endless hours discussing mechanistic details! Cheers!🥂 (13/13)
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David Walzik @davidwalzik.bsky.social · 04/12/2024
As always this project would not have been possible without the help of numerous collaborators. A special thanks to @50823zimmer.bsky.social , Alan Metcalfe and @niklasjoisten.bsky.social who planned and conducted the trials and to Alexander Schenk, who performed hundreds of PCRs. (12/13)
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eLife @elife.bsky.social · 26/11/2024
6/ Writing or reviewing a manuscript? Watch out for these ten common statistical mistakes 👇 elifesciences.org/articles/48175?ut…
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Alexander Bartelt @barteltlab.bsky.social · 30/11/2024
Recently, I have been on a grant review panel and a few members judged applications by the PI’s H index and impact factor of the previous papers - I objected. What has that to do with the strength of the proposed project?
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