Many RNA viruses can leave persistent RNA or proteins in tissues after acute infection.
This may help drive long term inflammation and post viral illness including Long COVID when the immune system cannot fully clear viral material.
www.nature.com/articles/s41...
nature.com
Implications of RNA virus persistence for post-acute sequelae and chronic inflammatory syndromes - Nature Immunology
López and colleagues review recent evidence of RNA virus persistence and the associated consequences in terms of post-acute sequelae or chronic inflammatory syndromes.