Excited to see our review is out @wileyonlinelibrary.bsky.social on CHD chromatin remodelers! We cover their roles in ES cells and early development in health and disease. Thanks to @hainerlab.bsky.social for her insight and guidance.
#chromatin #Epigenetics
@hainerlab.bsky.socialThe talented @isa-ozdemir.bsky.social wrote a review of CHD remodelers, discussing all 9 family members and their roles in ES cells and early development. dx.doi.org/10.1002/bies... 1/2
dx.doi.org
Molecular Acrobats: How CHD Remodelers Shape the Genetic Playground to License Cell Identity
In eukaryotes, DNA is not a naked repository of genetic information but is tightly wound around histone octamers to form nucleosomes. While this packaging solves the spatial problem of fitting 2 mete...