Maria Hondele @mariahondele.bsky.social · 03/08/2026Loss of PAIP1 alters cytoplasmic mRNP composition, mRNA stability, and poly(A)-tail homeostasis. In Drosophila embryos, maternal PAIP1 depletion shortens poly(A) tails, delays zygotic genome activation, and causes severe developmental defects. 120
Maria Hondele @mariahondele.bsky.social · 03/08/2026This would not have been possible without our fantastic collaborators, especially @kellervalsecchi.bsky.social & Martin for the beautiful 🪰 work and many great discussions, and @mihaelazavolan.bsky.social, Aleksei & Robert for helping us perform and interpret our very first sequencing experiments. 030
