Riccardo Bocchi @bocchiric.bsky.social · 31/07/20253/ Lineage 1 🟦: Emx1⁺ radial glia → neurons first, astrocytes later. Lineage 2 🟥: Emx1⁻ radial glia → few neurons, mostly astrocytes. Each lineage gives rise to different astrocyte subtypes — with unique locations and functions. 100 0
Riccardo Bocchi @bocchiric.bsky.social · 31/07/20254/ Why does this matter? Because astrocyte origin shapes astrocyte function. Olig2-lineage astrocytes are synaptogenic — they promote synapse formation. Knock out Olig2, and synaptic density drops. 100 0
Riccardo Bocchi @bocchiric.bsky.social · 31/07/20255/ ⭐️ This study reshapes our understanding of how astrocyte diversity emerges during cortical development. 100 0
