ME/CFS Science @mecfsscience.org · 11/09/20266) The results for red blood cell volume (RBCV) were as follows: 49% had an RBCV deficit 41% had normal RBCV 10% had RBCV excess. Reduced RBCV points to less circulating red cell mass and can point to (occult) anemia. 190
ME/CFS Science @mecfsscience.org · 11/09/20267) On the lean test, 12% had POTS, 40% had postural orthostatic syndrome of hypocapnia (POSH) and another 8% had both POTS and POSH. These outcomes, however, were not related to total blood volume or RBCV. 190
ME/CFS Science @mecfsscience.org · 11/09/20268) The authors write: "These findings suggest that static blood volume deficits alone are unlikely to be the principal determinant of OI in ME/CFS" They also point to a 2001 trial of fludrocortisone, a drug that increases blood volume but which showed only limited benefit. 190