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ME/CFS Science @mecfsscience.org · 01/09/2026

4) IMHO the core problem is what to do with patients who have orthostatic intolerance symptoms and disability without a known cause and without clear signs of dysautonomia. The distinction between those with and without orthostatic tachycardia (POTS or not) may be less important

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ME/CFS Science @mecfsscience.org · 01/09/2026

5) You can see this in the consensus statement which argue that both groups may have similar impairments, symptoms and that the same treatments may be useful for both. Orthostatic tachycardia is a useful clinical feature but perhaps not sufficient to base a syndrome on.

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ME/CFS Science @mecfsscience.org · 01/09/2026

6) The panel of 40 experts formulated several other consensus statements, including for example, that "POTS and other autonomic disorders are not functional neurologic disorders" and that POTS is not caused by fear of standing or avoidance behavior.

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