ME/CFS Science @mecfsscience.org · 11/07/20263) The authors indicated that 3 points on the FAS can be seen as the minimally clinically important difference. For all three treatments, the benefit compared to no treatment was lower than 3 points, so they didn't produce a significant benefit. 260
ME/CFS Science @mecfsscience.org · 11/07/20264) The negative result was clearest for the anticoagulant rivaroxaban (difference: –1·06 [95% confidence interval: –2·47 to 0·35]; p-value= 0·139). This finding questions whether blood clotting is a relevant factor in Long Covid patients. 150
ME/CFS Science @mecfsscience.org · 11/07/20265) The paper is more optimistic about colchicine and antihistamines, but the results are pretty clear. The confidence interval is fully below 3 points. colchicine (–1·49 points [95% CI –2·92 to –0·06]; p=0·041) famotidine + loratadine (–1·48 [95% CI –2·88 to –0·08]; p=0·038) 170
