iiinova — where your digital self keeps evolving

Replies

ME/CFS Science @mecfsscience.org · 03/04/2026

6) The COGNITIVE group tested the percentage that improved by 5 points or more on the PROMIS Cognitive 8a questionnaire T scale. This was 57.8% in the Paxlovid and 54.6% in the placebo group. The difference was not statistically significant (p-value = 0.646).

190

ME/CFS Science @mecfsscience.org · 03/04/2026

7) There was also an objective outcome: the Neurocognitive Battery (a series of cognitive tests). The percentage with a meaningful improvement here was 9.8% in the Paxlovid group and 14.3% in the placebo group (p-value: 0.317).

180

ME/CFS Science @mecfsscience.org · 03/04/2026

8) The AUTONOMIC group tested the percentage that improved by at least 1 point on the Orthostatic Hypotension Questionnaire (OHQ). This was 63.1% in the Paxlovid group compared to 69.5% in the placebo group (p-value: 0.303). So, no benefit here either.

1100