ME/CFS Science @mecfsscience.org · 18/10/20256) It's unclear, however, if this model fits ME/CFS. At high expression of ACOD1, the fish also showed a reduced heart rate and signs of cardiac impairment. 260
ME/CFS Science @mecfsscience.org · 18/10/20257) Lastly, they tested multiple ACOD1 inhibitors and found that some restored movement in the zebrafish back to a normal amount. So if the Itaconate shunt model is correct, this could be a potential treatment. 170
ME/CFS Science @mecfsscience.org · 18/10/20258 ) The full presentation can be watched here:youtube.comRandall Peterson, PhD | Using zebrafish to model metabolic changes related to fatigueRandall Peterson, PhD, University of Utah Using zebrafish to model metabolic changes related to fatigue 061
