ME/CFS Science @mecfsscience.org · 08/05/20255) The authors also looked at markers of mitochondrial activity such as SDH (succinate dehydrogenase) and oxidative phosphorylation. These strongly correlated with VO2max in bed rest participants but not or much less so in ME/CFS or LC patients. 1131
ME/CFS Science @mecfsscience.org · 08/05/20256) The authors write: "The lack of association of VO2max with mitochondrial variables suggests that their reduced exercise capacity is not solely explained by mitochondrial respiration or enzymatic activity." 1111
ME/CFS Science @mecfsscience.org · 08/05/20257) There were also some unexpected findings. The authors expected myoglobin (a protein that binds oxygen) to be increased in patients to compensate for a reduced local oxygen supply. But it was increased in bed rest participants, not in ME/CFS patients. 1110
