ME/CFS Science @mecfsscience.org · 08/05/20254) In the bed rest participants, capillary density - the number of tiny blood vessels per area of muscle tissue - increased while in ME/CFS patients it decreased. 1132
ME/CFS Science @mecfsscience.org · 08/05/20255) The authors also looked at markers of mitochondrial activity such as SDH (succinate dehydrogenase) and oxidative phosphorylation. These strongly correlated with VO2max in bed rest participants but not or much less so in ME/CFS or LC patients. 1131
ME/CFS Science @mecfsscience.org · 08/05/20256) The authors write: "The lack of association of VO2max with mitochondrial variables suggests that their reduced exercise capacity is not solely explained by mitochondrial respiration or enzymatic activity." 1111