ME/CFS Science @mecfsscience.org · 13/01/20255) This is quite vague as it doesn’t define which symptoms get worse, how long after the effort, and if it caused additional functional impairment. It was also a yes/no question, severity of PEM was not measured. 150
ME/CFS Science @mecfsscience.org · 13/01/20256) Orthostatic intolerance was queried by asking if participants had the following: “Feeling faint, dizzy, ‘goofy’; difficulty thinking soon after standing up from a sitting or lying position” 140
ME/CFS Science @mecfsscience.org · 13/01/20257) I think these limitations explain why some of the estimates were quite high. The incidence rate of 2.66 per 100 person-years, for example, is more than 10x that of previous estimates. 140
